Importance of resting heart rate
Olshansky, Brian ; Ricci, Fabrizio LU and Fedorowski, Artur LU
(2023)
In Trends in Cardiovascular Medicine
33(8).
p.502-515
- Abstract
Resting heart rate is a determinant of cardiac output and physiological homeostasis. Although a simple, but critical, parameter, this vital sign predicts adverse outcomes, including mortality, and development of diseases in otherwise normal and healthy individuals. Temporal changes in heart rate can have valuable predictive capabilities. Heart rate can reflect disease severity in patients with various medical conditions. While heart rate represents a compilation of physiological inputs, including sympathetic and parasympathetic tone, aside from the underlying intrinsic sinus rate, how resting heart rate affects outcomes is uncertain. Mechanisms relating resting heart rate to outcomes may be disease-dependent but why resting heart rate... (More)
Resting heart rate is a determinant of cardiac output and physiological homeostasis. Although a simple, but critical, parameter, this vital sign predicts adverse outcomes, including mortality, and development of diseases in otherwise normal and healthy individuals. Temporal changes in heart rate can have valuable predictive capabilities. Heart rate can reflect disease severity in patients with various medical conditions. While heart rate represents a compilation of physiological inputs, including sympathetic and parasympathetic tone, aside from the underlying intrinsic sinus rate, how resting heart rate affects outcomes is uncertain. Mechanisms relating resting heart rate to outcomes may be disease-dependent but why resting heart rate in otherwise healthy, normal individuals affects outcomes remains obscure. For specific conditions, physiologically appropriate heart rate reductions may improve outcomes. However, to date, in the normal population, evidence that interventions aimed at reducing heart rate improves outcomes remains undefined. Emerging data suggest that reduction in heart rate via vagal activation and/or sympathetic inhibition is propitious.
(Less)
- author
- Olshansky, Brian
; Ricci, Fabrizio
LU
and Fedorowski, Artur
LU
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Trends in Cardiovascular Medicine
- volume
- 33
- issue
- 8
- pages
- 502 - 515
- publisher
- Elsevier
- external identifiers
-
- pmid:35623552
- scopus:85131243320
- ISSN
- 1873-2615
- DOI
- 10.1016/j.tcm.2022.05.006
- language
- English
- LU publication?
- yes
- additional info
- Copyright © 2022. Published by Elsevier Inc.
- id
- 5476abb5-1d41-4101-af36-4afb66b26655
- date added to LUP
- 2022-06-03 16:21:38
- date last changed
- 2024-06-13 09:32:37
@article{5476abb5-1d41-4101-af36-4afb66b26655,
abstract = {{<p>Resting heart rate is a determinant of cardiac output and physiological homeostasis. Although a simple, but critical, parameter, this vital sign predicts adverse outcomes, including mortality, and development of diseases in otherwise normal and healthy individuals. Temporal changes in heart rate can have valuable predictive capabilities. Heart rate can reflect disease severity in patients with various medical conditions. While heart rate represents a compilation of physiological inputs, including sympathetic and parasympathetic tone, aside from the underlying intrinsic sinus rate, how resting heart rate affects outcomes is uncertain. Mechanisms relating resting heart rate to outcomes may be disease-dependent but why resting heart rate in otherwise healthy, normal individuals affects outcomes remains obscure. For specific conditions, physiologically appropriate heart rate reductions may improve outcomes. However, to date, in the normal population, evidence that interventions aimed at reducing heart rate improves outcomes remains undefined. Emerging data suggest that reduction in heart rate via vagal activation and/or sympathetic inhibition is propitious.</p>}},
author = {{Olshansky, Brian and Ricci, Fabrizio and Fedorowski, Artur}},
issn = {{1873-2615}},
language = {{eng}},
number = {{8}},
pages = {{502--515}},
publisher = {{Elsevier}},
series = {{Trends in Cardiovascular Medicine}},
title = {{Importance of resting heart rate}},
url = {{http://dx.doi.org/10.1016/j.tcm.2022.05.006}},
doi = {{10.1016/j.tcm.2022.05.006}},
volume = {{33}},
year = {{2023}},
}