Advanced

Bioactive Pt(II) and Au(I) complexes based on 1,1’-bis(diphenylphosphino)metallocene derivatives

Bjelosevic, Haris LU ; Guzei, Ilia A. ; Spencer, Lara C. ; Darkwa, James ; Persson, Tina LU and Elmroth, Sofi LU (2008) In Historielärarnas Förenings Årsskrift
Abstract
New 1,2,1’ substituted bis(diphenylphoshino)ruthenocenes are described and used as ligands in cis-Pt(II) complexes. The new substances were also employed in Au(I) complexes, together with previously described ferrocene-based ligands. Examples of crystal structures are presented for the ligands, as well as for the platinum and gold complexes. The preliminary biological activity covering antitumour, antiviral and antimalarial properties of new gold(I) complexes were very promising.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
unpublished
subject
keywords
bioactive, anticancer, metallocenes, gold, platinum, antiviral
in
Historielärarnas Förenings Årsskrift
publisher
Historielärarnas förening
ISSN
0439-2434
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Biochemistry and Structural Biology (S) (000006142), Organic chemistry (S/LTH) (011001240)
id
5923957f-9441-42ad-8609-30e72d93ff25 (old id 1241933)
date added to LUP
2016-04-04 12:58:52
date last changed
2019-11-25 09:03:47
@article{5923957f-9441-42ad-8609-30e72d93ff25,
  abstract     = {New 1,2,1’ substituted bis(diphenylphoshino)ruthenocenes are described and used as ligands in cis-Pt(II) complexes. The new substances were also employed in Au(I) complexes, together with previously described ferrocene-based ligands. Examples of crystal structures are presented for the ligands, as well as for the platinum and gold complexes. The preliminary biological activity covering antitumour, antiviral and antimalarial properties of new gold(I) complexes were very promising.},
  author       = {Bjelosevic, Haris and Guzei, Ilia A. and Spencer, Lara C. and Darkwa, James and Persson, Tina and Elmroth, Sofi},
  issn         = {0439-2434},
  language     = {eng},
  publisher    = {Historielärarnas förening},
  series       = {Historielärarnas Förenings Årsskrift},
  title        = {Bioactive Pt(II) and Au(I) complexes based on 1,1’-bis(diphenylphosphino)metallocene derivatives},
  url          = {https://lup.lub.lu.se/search/ws/files/6031050/1241935.pdf},
  year         = {2008},
}