PVC flooring is related to human uptake of phthalates in infants.
(2012) In Indoor Air- Abstract
- Poly Vinyl Chloride (PVC) flooring material contains phthalates and it has been shown that such materials are important sources for phthalates in indoor dust. Phthalates are suspected endocrine disrupting chemicals (EDCs). Consecutive infants between two and six months old and their mothers were invited. A questionnaire about indoor environmental factors and family life style was used. Urinary metabolites of the phthalates di-ethyl phthalate (DEP), di-butyl phthalate (DBP), butylbenzyl phthalate (BBzP) and di-etylhexyl phthalate (DEHP) were measured in the urine of the children. Of 209 invited children, 110 (52%) participated. Urine samples were obtained from 83 of these. Urine levels of the BBzP metabolite monobenzyl phthalate (MBzP) was... (More)
- Poly Vinyl Chloride (PVC) flooring material contains phthalates and it has been shown that such materials are important sources for phthalates in indoor dust. Phthalates are suspected endocrine disrupting chemicals (EDCs). Consecutive infants between two and six months old and their mothers were invited. A questionnaire about indoor environmental factors and family life style was used. Urinary metabolites of the phthalates di-ethyl phthalate (DEP), di-butyl phthalate (DBP), butylbenzyl phthalate (BBzP) and di-etylhexyl phthalate (DEHP) were measured in the urine of the children. Of 209 invited children, 110 (52%) participated. Urine samples were obtained from 83 of these. Urine levels of the BBzP metabolite monobenzyl phthalate (MBzP) was significantly higher in infants with PVC flooring in their bedrooms (p<0.007) and related to the body area of the infant. Levels of the DEHP metabolites MEHHP (p<0.01) and MEOHP (p<0.04) were higher in the two months old infants who were not exclusively breastfed when compared with breastfed children. The findings indicate that the use of soft PVC as flooring material may increase the human uptake of phthalates in infants. Urinary levels of phthalate metabolites during early life are associated to the use of PVC flooring in the bedroom, body area and the use of infant formula. © 2012 John Wiley & Sons A/S. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2609052
- author
- Carlstedt, Fredrik ; Jönsson, Bo A LU and Bornehag, Carl-Gustaf
- organization
- publishing date
- 2012-05-07
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Indoor Air
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000313594000005
- pmid:22563949
- scopus:84872372920
- pmid:22563949
- ISSN
- 0905-6947
- DOI
- 10.1111/j.1600-0668.2012.00788.x
- language
- English
- LU publication?
- yes
- id
- 5f18b23e-1f72-4951-a765-91b68033faba (old id 2609052)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22563949?dopt=Abstract
- date added to LUP
- 2016-04-04 09:22:29
- date last changed
- 2022-04-08 02:42:44
@article{5f18b23e-1f72-4951-a765-91b68033faba, abstract = {{Poly Vinyl Chloride (PVC) flooring material contains phthalates and it has been shown that such materials are important sources for phthalates in indoor dust. Phthalates are suspected endocrine disrupting chemicals (EDCs). Consecutive infants between two and six months old and their mothers were invited. A questionnaire about indoor environmental factors and family life style was used. Urinary metabolites of the phthalates di-ethyl phthalate (DEP), di-butyl phthalate (DBP), butylbenzyl phthalate (BBzP) and di-etylhexyl phthalate (DEHP) were measured in the urine of the children. Of 209 invited children, 110 (52%) participated. Urine samples were obtained from 83 of these. Urine levels of the BBzP metabolite monobenzyl phthalate (MBzP) was significantly higher in infants with PVC flooring in their bedrooms (p<0.007) and related to the body area of the infant. Levels of the DEHP metabolites MEHHP (p<0.01) and MEOHP (p<0.04) were higher in the two months old infants who were not exclusively breastfed when compared with breastfed children. The findings indicate that the use of soft PVC as flooring material may increase the human uptake of phthalates in infants. Urinary levels of phthalate metabolites during early life are associated to the use of PVC flooring in the bedroom, body area and the use of infant formula. © 2012 John Wiley & Sons A/S.}}, author = {{Carlstedt, Fredrik and Jönsson, Bo A and Bornehag, Carl-Gustaf}}, issn = {{0905-6947}}, language = {{eng}}, month = {{05}}, publisher = {{Wiley-Blackwell}}, series = {{Indoor Air}}, title = {{PVC flooring is related to human uptake of phthalates in infants.}}, url = {{http://dx.doi.org/10.1111/j.1600-0668.2012.00788.x}}, doi = {{10.1111/j.1600-0668.2012.00788.x}}, year = {{2012}}, }