Predictors of acute myocardial infarction mortality in hypertensive patients treated in primary care.
(2007) In Scandinavian Journal of Primary Health Care 25(4). p.237-243- Abstract
- Objective. To explore risk factors for acute myocardial infarction (AMI) mortality in hypertensive patients treated in primary care. Design. Community-based cohort study. Setting. Hypertension outpatient clinic in primary health care. Subjects. Patients who consecutively underwent an annual follow-up during 1992-1993 (n =894; 377 men and 517 women). Methods. All events of fatal AMI were ascertained by record linkage to the National Mortality Register to December 31, 2002. Gender-specific predictors for AMI mortality were analysed by Cox regression. Main outcome measure. AMI mortality. Results. During a mean follow-up of 8.7 years 32 cases (8.5%) of fatal AMI were observed in men and 31 cases (6.0%) were observed in women. Most important... (More)
- Objective. To explore risk factors for acute myocardial infarction (AMI) mortality in hypertensive patients treated in primary care. Design. Community-based cohort study. Setting. Hypertension outpatient clinic in primary health care. Subjects. Patients who consecutively underwent an annual follow-up during 1992-1993 (n =894; 377 men and 517 women). Methods. All events of fatal AMI were ascertained by record linkage to the National Mortality Register to December 31, 2002. Gender-specific predictors for AMI mortality were analysed by Cox regression. Main outcome measure. AMI mortality. Results. During a mean follow-up of 8.7 years 32 cases (8.5%) of fatal AMI were observed in men and 31 cases (6.0%) were observed in women. Most important predictors for AMI mortality in men were microalbuminuria (HR 3.8, CI 1.8-8.0) and left ventricular hypertrophy (HR 4.0, CI 1.7-9.4), whilst in women type 2 diabetes (HR 4.8, CI 2.4-9.8) was an important predictor. In hypertensive patients without diabetes male gender was associated with high AMI mortality (HR 2.7, CI 1.4-5.3), but in patients with both hypertension and type 2 diabetes the higher risk in men disappeared (HR 0.8, CI 0.4-1.7). Conclusion. Cardiovascular disease risk factors remain strong predictors of AMI mortality in hypertensive patients but with a different pattern in the two genders. Markers of organ damage are more important predictors in men, whereas markers of impaired glucose metabolism are more important predictors in women. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/608249
- author
- Bøg-Hansen, Erik LU ; Larsson, Charlotte A LU ; Gullberg, Bo LU ; Melander, Arne LU ; Bengtsson Boström, Kristina LU ; Råstam, Lennart LU and Lindblad, Ulf LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Acute myocardial infarction, cardiovascular disease risk factors, family practice, hypertension, primary care, type 2 diabetes
- in
- Scandinavian Journal of Primary Health Care
- volume
- 25
- issue
- 4
- pages
- 237 - 243
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000252846800010
- scopus:36549062990
- ISSN
- 0281-3432
- DOI
- 10.1080/02813430701706253
- language
- English
- LU publication?
- yes
- id
- 0821ed6c-8e9f-455c-88f4-4e7b6cf1204f (old id 608249)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17965983&dopt=Abstract
- date added to LUP
- 2016-04-01 12:28:40
- date last changed
- 2022-03-06 00:05:48
@article{0821ed6c-8e9f-455c-88f4-4e7b6cf1204f,
abstract = {{Objective. To explore risk factors for acute myocardial infarction (AMI) mortality in hypertensive patients treated in primary care. Design. Community-based cohort study. Setting. Hypertension outpatient clinic in primary health care. Subjects. Patients who consecutively underwent an annual follow-up during 1992-1993 (n =894; 377 men and 517 women). Methods. All events of fatal AMI were ascertained by record linkage to the National Mortality Register to December 31, 2002. Gender-specific predictors for AMI mortality were analysed by Cox regression. Main outcome measure. AMI mortality. Results. During a mean follow-up of 8.7 years 32 cases (8.5%) of fatal AMI were observed in men and 31 cases (6.0%) were observed in women. Most important predictors for AMI mortality in men were microalbuminuria (HR 3.8, CI 1.8-8.0) and left ventricular hypertrophy (HR 4.0, CI 1.7-9.4), whilst in women type 2 diabetes (HR 4.8, CI 2.4-9.8) was an important predictor. In hypertensive patients without diabetes male gender was associated with high AMI mortality (HR 2.7, CI 1.4-5.3), but in patients with both hypertension and type 2 diabetes the higher risk in men disappeared (HR 0.8, CI 0.4-1.7). Conclusion. Cardiovascular disease risk factors remain strong predictors of AMI mortality in hypertensive patients but with a different pattern in the two genders. Markers of organ damage are more important predictors in men, whereas markers of impaired glucose metabolism are more important predictors in women.}},
author = {{Bøg-Hansen, Erik and Larsson, Charlotte A and Gullberg, Bo and Melander, Arne and Bengtsson Boström, Kristina and Råstam, Lennart and Lindblad, Ulf}},
issn = {{0281-3432}},
keywords = {{Acute myocardial infarction; cardiovascular disease risk factors; family practice; hypertension; primary care; type 2 diabetes}},
language = {{eng}},
number = {{4}},
pages = {{237--243}},
publisher = {{Taylor & Francis}},
series = {{Scandinavian Journal of Primary Health Care}},
title = {{Predictors of acute myocardial infarction mortality in hypertensive patients treated in primary care.}},
url = {{http://dx.doi.org/10.1080/02813430701706253}},
doi = {{10.1080/02813430701706253}},
volume = {{25}},
year = {{2007}},
}