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Biological monitoring of toluene diisocyanate (TDI) exposure by analysis of urine from exposed workers

Lindh, Christian LU ; Sennbro, Carl Johan LU ; Tinnerberg, Håkan LU ; Welinder, Hans LU and Jönsson, Bo A LU (2002) Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics p.655-656
Abstract
A gas chromatography-negative ion chemical ionization-selected ion monitoring-mass spectrometry (GC-NICI-SIM-MS) method was used to quantitate the metabolite toluene diamine (TDA) in urine samples of toluene diisocyanate (TDI) exposed workers. In order to validate the biological monitoring method, air samples were collected and analyzed using a liquid chromatography tandem mass spectrometry (LC-MS) method. The urine samples were treated with liquid-liquid extraction to retrieve the toluene diamine (TDA). It was observed that urinary TDA levels were applicable fro biological monitoring of TDI exposure.
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author
; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Liquid-liquid extraction, Toluence diisocyanate (TDI), Toluene diamine (TDA), Time weighted average (TWA)
host publication
Proceedings 50th ASMS Conference on Mass Spectrmetry and Allied Topics
pages
655 - 656
publisher
American Society for Mass Spectrometry, Santa Fe, NM, 87505, United States
conference name
Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
conference location
Orlando, FL, United States
conference dates
2002-06-02 - 2002-06-06
external identifiers
  • scopus:2442658124
language
English
LU publication?
yes
id
1c163db3-284f-4777-b185-f05728e233fc (old id 611108)
date added to LUP
2016-04-04 12:00:26
date last changed
2020-01-12 21:32:14
@inproceedings{1c163db3-284f-4777-b185-f05728e233fc,
  abstract     = {A gas chromatography-negative ion chemical ionization-selected ion monitoring-mass spectrometry (GC-NICI-SIM-MS) method was used to quantitate the metabolite toluene diamine (TDA) in urine samples of toluene diisocyanate (TDI) exposed workers. In order to validate the biological monitoring method, air samples were collected and analyzed using a liquid chromatography tandem mass spectrometry (LC-MS) method. The urine samples were treated with liquid-liquid extraction to retrieve the toluene diamine (TDA). It was observed that urinary TDA levels were applicable fro biological monitoring of TDI exposure.},
  author       = {Lindh, Christian and Sennbro, Carl Johan and Tinnerberg, Håkan and Welinder, Hans and Jönsson, Bo A},
  booktitle    = {Proceedings 50th ASMS Conference on Mass Spectrmetry and Allied Topics},
  language     = {eng},
  pages        = {655--656},
  publisher    = {American Society for Mass Spectrometry, Santa Fe, NM, 87505, United States},
  title        = {Biological monitoring of toluene diisocyanate (TDI) exposure by analysis of urine from exposed workers},
  year         = {2002},
}