Biological monitoring of toluene diisocyanate (TDI) exposure by analysis of urine from exposed workers
(2002) Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics p.655-656- Abstract
- A gas chromatography-negative ion chemical ionization-selected ion monitoring-mass spectrometry (GC-NICI-SIM-MS) method was used to quantitate the metabolite toluene diamine (TDA) in urine samples of toluene diisocyanate (TDI) exposed workers. In order to validate the biological monitoring method, air samples were collected and analyzed using a liquid chromatography tandem mass spectrometry (LC-MS) method. The urine samples were treated with liquid-liquid extraction to retrieve the toluene diamine (TDA). It was observed that urinary TDA levels were applicable fro biological monitoring of TDI exposure.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/611108
- author
- Lindh, Christian LU ; Sennbro, Carl Johan LU ; Tinnerberg, Håkan LU ; Welinder, Hans LU and Jönsson, Bo A LU
- organization
- publishing date
- 2002
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Liquid-liquid extraction, Toluence diisocyanate (TDI), Toluene diamine (TDA), Time weighted average (TWA)
- host publication
- Proceedings 50th ASMS Conference on Mass Spectrmetry and Allied Topics
- pages
- 655 - 656
- publisher
- American Society for Mass Spectrometry, Santa Fe, NM, 87505, United States
- conference name
- Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
- conference location
- Orlando, FL, United States
- conference dates
- 2002-06-02 - 2002-06-06
- external identifiers
-
- scopus:2442658124
- language
- English
- LU publication?
- yes
- id
- 1c163db3-284f-4777-b185-f05728e233fc (old id 611108)
- date added to LUP
- 2016-04-04 12:00:26
- date last changed
- 2022-02-13 22:09:56
@inproceedings{1c163db3-284f-4777-b185-f05728e233fc, abstract = {{A gas chromatography-negative ion chemical ionization-selected ion monitoring-mass spectrometry (GC-NICI-SIM-MS) method was used to quantitate the metabolite toluene diamine (TDA) in urine samples of toluene diisocyanate (TDI) exposed workers. In order to validate the biological monitoring method, air samples were collected and analyzed using a liquid chromatography tandem mass spectrometry (LC-MS) method. The urine samples were treated with liquid-liquid extraction to retrieve the toluene diamine (TDA). It was observed that urinary TDA levels were applicable fro biological monitoring of TDI exposure.}}, author = {{Lindh, Christian and Sennbro, Carl Johan and Tinnerberg, Håkan and Welinder, Hans and Jönsson, Bo A}}, booktitle = {{Proceedings 50th ASMS Conference on Mass Spectrmetry and Allied Topics}}, keywords = {{Liquid-liquid extraction; Toluence diisocyanate (TDI); Toluene diamine (TDA); Time weighted average (TWA)}}, language = {{eng}}, pages = {{655--656}}, publisher = {{American Society for Mass Spectrometry, Santa Fe, NM, 87505, United States}}, title = {{Biological monitoring of toluene diisocyanate (TDI) exposure by analysis of urine from exposed workers}}, year = {{2002}}, }