Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Does Allergen-specific Immunotherapy Induce Contact Allergy to Aluminium?

Netterlid, Eva LU ; Hindsén, Monica LU ; Siemund, Ingrid LU ; Björk, Jonas LU ; Werner, Sonja LU ; Jacobsson, Helene ; Güner, Nuray and Bruze, Magnus LU (2013) In Acta Dermato-Venereologica 93. p.50-56
Abstract
Persistent, itching nodules have been reported to appear at the injection site after allergen-specific immuno-therapy with aluminium-precipitated antigen extract, occasionally in conjunction with contact allergy to aluminium. This study aimed to quantify the development of contact allergy to aluminium during allergen-specific immunotherapy. A randomized, controlled, single-blind multicentre study of children and adults entering allergen-specific immunotherapy was performed using questionnaires and patch-testing. A total of 205 individuals completed the study. In the 3 study groups all subjects tested negative to aluminium before allergen-specific immunotherapy and 4 tested positive after therapy. In the control group 4 participants tested... (More)
Persistent, itching nodules have been reported to appear at the injection site after allergen-specific immuno-therapy with aluminium-precipitated antigen extract, occasionally in conjunction with contact allergy to aluminium. This study aimed to quantify the development of contact allergy to aluminium during allergen-specific immunotherapy. A randomized, controlled, single-blind multicentre study of children and adults entering allergen-specific immunotherapy was performed using questionnaires and patch-testing. A total of 205 individuals completed the study. In the 3 study groups all subjects tested negative to aluminium before allergen-specific immunotherapy and 4 tested positive after therapy. In the control group 4 participants tested positive to aluminium. Six out of 8 who tested positive also had atopic dermatitis. Positive test results were found in 5/78 children and 3/127 adults. Allergen-specific immunotherapy was not shown to be a risk factor for contact allergy to aluminium. Among those who did develop aluminium allergy, children and those with atopic dermatitis were more highly represented. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
93
pages
50 - 56
publisher
Medical Journals Limited
external identifiers
  • wos:000313373300010
  • pmid:22948339
  • scopus:84871695361
  • pmid:22948339
ISSN
1651-2057
DOI
10.2340/00015555-1409
language
English
LU publication?
yes
id
63aa4c6e-0d52-40ba-b29e-dd3e1c8173c4 (old id 3124359)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22948339?dopt=Abstract
date added to LUP
2016-04-01 14:09:09
date last changed
2022-03-14 03:50:43
@article{63aa4c6e-0d52-40ba-b29e-dd3e1c8173c4,
  abstract     = {{Persistent, itching nodules have been reported to appear at the injection site after allergen-specific immuno-therapy with aluminium-precipitated antigen extract, occasionally in conjunction with contact allergy to aluminium. This study aimed to quantify the development of contact allergy to aluminium during allergen-specific immunotherapy. A randomized, controlled, single-blind multicentre study of children and adults entering allergen-specific immunotherapy was performed using questionnaires and patch-testing. A total of 205 individuals completed the study. In the 3 study groups all subjects tested negative to aluminium before allergen-specific immunotherapy and 4 tested positive after therapy. In the control group 4 participants tested positive to aluminium. Six out of 8 who tested positive also had atopic dermatitis. Positive test results were found in 5/78 children and 3/127 adults. Allergen-specific immunotherapy was not shown to be a risk factor for contact allergy to aluminium. Among those who did develop aluminium allergy, children and those with atopic dermatitis were more highly represented.}},
  author       = {{Netterlid, Eva and Hindsén, Monica and Siemund, Ingrid and Björk, Jonas and Werner, Sonja and Jacobsson, Helene and Güner, Nuray and Bruze, Magnus}},
  issn         = {{1651-2057}},
  language     = {{eng}},
  pages        = {{50--56}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Does Allergen-specific Immunotherapy Induce Contact Allergy to Aluminium?}},
  url          = {{https://lup.lub.lu.se/search/files/3817147/3602660.pdf}},
  doi          = {{10.2340/00015555-1409}},
  volume       = {{93}},
  year         = {{2013}},
}