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Diels-Alder adducts derived from the natural phthalide Z-ligustilide

Lager, Erik LU ; Sundin, Anders LU ; Toscano, Ruben A. ; Delgado, Guillermo and Sterner, Olov LU (2007) In Tetrahedron Letters 48(24). p.4215-4218
Abstract
Z-Ligustilide, a naturally occurring phthalide isolated from Ligusticum porteri, underwent Diels-Alder reactions with different dienophiles yielding novel tricyclic products with potentially interesting biological properties. Where selectivity was possible, the reactions performed showed regio- and stereoselectivity. The experimental results with ethyl acrylate were compared with the selectivity predicted by ab initio calculations.
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
STAT3, Z-ligustilide, galiellalactone, ab initio, Diels-Alder
in
Tetrahedron Letters
volume
48
issue
24
pages
4215 - 4218
publisher
Elsevier
external identifiers
  • wos:000247225800014
  • scopus:34249025719
ISSN
0040-4039
DOI
10.1016/j.tetlet.2007.04.059
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
id
eafcc48d-5f20-4bc4-b396-7f149f510656 (old id 648643)
date added to LUP
2016-04-01 16:18:57
date last changed
2022-01-28 18:50:26
@article{eafcc48d-5f20-4bc4-b396-7f149f510656,
  abstract     = {{Z-Ligustilide, a naturally occurring phthalide isolated from Ligusticum porteri, underwent Diels-Alder reactions with different dienophiles yielding novel tricyclic products with potentially interesting biological properties. Where selectivity was possible, the reactions performed showed regio- and stereoselectivity. The experimental results with ethyl acrylate were compared with the selectivity predicted by ab initio calculations.}},
  author       = {{Lager, Erik and Sundin, Anders and Toscano, Ruben A. and Delgado, Guillermo and Sterner, Olov}},
  issn         = {{0040-4039}},
  keywords     = {{STAT3; Z-ligustilide; galiellalactone; ab initio; Diels-Alder}},
  language     = {{eng}},
  number       = {{24}},
  pages        = {{4215--4218}},
  publisher    = {{Elsevier}},
  series       = {{Tetrahedron Letters}},
  title        = {{Diels-Alder adducts derived from the natural phthalide Z-ligustilide}},
  url          = {{http://dx.doi.org/10.1016/j.tetlet.2007.04.059}},
  doi          = {{10.1016/j.tetlet.2007.04.059}},
  volume       = {{48}},
  year         = {{2007}},
}