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Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017 : An Official American Thoracic Society Workshop Report

Ryan, Amy L ; Ikonomou, Laertis ; Atarod, Sadaf ; Bölükbas, Deniz A LU ; Collins, Jennifer ; Freishtat, Rob ; Hawkins, Finn ; Gilpin, Sarah E ; Uhl, Franziska E LU and Uriarte, Juan Jose , et al. (2019) In American Journal of Respiratory Cell and Molecular Biology
Abstract

The University of Vermont Larner College of Medicine, in collaboration with the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 Foundation, the American Thoracic Society, the Cystic Fibrosis Foundation, the European Respiratory Society, the International Society for Cell & Gene Therapy, and the Pulmonary Fibrosis Foundation, convened a workshop titled "Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases" from July 24 through 27, 2017, at the University of Vermont, Burlington, Vermont. The conference objectives were to review and discuss current understanding of the following topics: 1) stem and progenitor cell biology and the role that they play in endogenous repair or as cell therapies after... (More)

The University of Vermont Larner College of Medicine, in collaboration with the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 Foundation, the American Thoracic Society, the Cystic Fibrosis Foundation, the European Respiratory Society, the International Society for Cell & Gene Therapy, and the Pulmonary Fibrosis Foundation, convened a workshop titled "Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases" from July 24 through 27, 2017, at the University of Vermont, Burlington, Vermont. The conference objectives were to review and discuss current understanding of the following topics: 1) stem and progenitor cell biology and the role that they play in endogenous repair or as cell therapies after lung injury, 2) the emerging role of extracellular vesicles as potential therapies, 3) ex vivo bioengineering of lung and airway tissue, and 4) progress in induced pluripotent stem cell protocols for deriving lung cell types and applications in disease modeling. All of these topics are research areas in which significant and exciting progress has been made over the past few years. In addition, issues surrounding the ethics and regulation of cell therapies worldwide were discussed, with a special emphasis on combating the growing problem of unproven cell interventions being administered to patients with lung diseases. Finally, future research directions were discussed, and opportunities for both basic and translational research were identified.

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type
Book/Report
publication status
published
subject
in
American Journal of Respiratory Cell and Molecular Biology
edition
4
pages
11 pages
report number
61
external identifiers
  • pmid:31573338
  • scopus:85072776745
ISSN
1535-4989
DOI
10.1165/rcmb.2019-0286ST
language
English
LU publication?
yes
id
656f55f4-b2ef-4633-9419-4fa013817f06
date added to LUP
2019-10-07 10:05:01
date last changed
2019-10-23 06:24:02
@techreport{656f55f4-b2ef-4633-9419-4fa013817f06,
  abstract     = {<p>The University of Vermont Larner College of Medicine, in collaboration with the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 Foundation, the American Thoracic Society, the Cystic Fibrosis Foundation, the European Respiratory Society, the International Society for Cell &amp; Gene Therapy, and the Pulmonary Fibrosis Foundation, convened a workshop titled "Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases" from July 24 through 27, 2017, at the University of Vermont, Burlington, Vermont. The conference objectives were to review and discuss current understanding of the following topics: 1) stem and progenitor cell biology and the role that they play in endogenous repair or as cell therapies after lung injury, 2) the emerging role of extracellular vesicles as potential therapies, 3) ex vivo bioengineering of lung and airway tissue, and 4) progress in induced pluripotent stem cell protocols for deriving lung cell types and applications in disease modeling. All of these topics are research areas in which significant and exciting progress has been made over the past few years. In addition, issues surrounding the ethics and regulation of cell therapies worldwide were discussed, with a special emphasis on combating the growing problem of unproven cell interventions being administered to patients with lung diseases. Finally, future research directions were discussed, and opportunities for both basic and translational research were identified.</p>},
  author       = {Ryan, Amy L and Ikonomou, Laertis and Atarod, Sadaf and Bölükbas, Deniz A and Collins, Jennifer and Freishtat, Rob and Hawkins, Finn and Gilpin, Sarah E and Uhl, Franziska E and Uriarte, Juan Jose and Weiss, Daniel J and Wagner, Darcy E},
  issn         = {1535-4989},
  language     = {eng},
  number       = {61},
  series       = {American Journal of Respiratory Cell and Molecular Biology},
  title        = {Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017 : An Official American Thoracic Society Workshop Report},
  url          = {http://dx.doi.org/10.1165/rcmb.2019-0286ST},
  doi          = {10.1165/rcmb.2019-0286ST},
  year         = {2019},
}