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Association between shift work history and performance on the trail making test in middle-aged and elderly humans : The EpiHealth study

Titova, Olga E.; Lindberg, Eva; Elmståhl, Sölve LU ; Lind, Lars; Schiöth, Helgi B. and Benedict, Christian (2016) In Neurobiology of Aging 45. p.23-29
Abstract

Shift work has been proposed to promote cognitive disturbances in humans; however, conflicting evidence is also present. By using data from 7143 middle-aged and elderly humans (45-75 years) who participated in the Swedish EpiHealth cohort study, the present analysis sought to investigate whether self-reported shift work history would be associated with performance on the trail making test (TMT). The TMT has been proposed to be a useful neuropsychological tool to evaluate humans' executive cognitive function, which is known to decrease with age. After adjustment for potential confounders (e.g., age, education, and sleep duration), it was observed that current and recent former shift workers (worked shifts during the past 5 years)... (More)

Shift work has been proposed to promote cognitive disturbances in humans; however, conflicting evidence is also present. By using data from 7143 middle-aged and elderly humans (45-75 years) who participated in the Swedish EpiHealth cohort study, the present analysis sought to investigate whether self-reported shift work history would be associated with performance on the trail making test (TMT). The TMT has been proposed to be a useful neuropsychological tool to evaluate humans' executive cognitive function, which is known to decrease with age. After adjustment for potential confounders (e.g., age, education, and sleep duration), it was observed that current and recent former shift workers (worked shifts during the past 5 years) performed worse on the TMT than nonshift workers. In contrast, performance on the TMT did not differ between past shift workers (off from shift work for more than 5 years) and nonshift workers. Collectively, our results indicate that shift work history is linked to poorer performance on the TMT in a cohort of middle-aged and elderly humans.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cohort study, Shift work history, Trail making test
in
Neurobiology of Aging
volume
45
pages
7 pages
publisher
Elsevier
external identifiers
  • Scopus:84973303667
  • WOS:000381092900003
ISSN
0197-4580
DOI
10.1016/j.neurobiolaging.2016.05.007
language
English
LU publication?
yes
id
678629cb-54ef-45c2-9793-14c1da48b674
date added to LUP
2016-07-06 14:32:26
date last changed
2017-01-01 08:29:54
@article{678629cb-54ef-45c2-9793-14c1da48b674,
  abstract     = {<p>Shift work has been proposed to promote cognitive disturbances in humans; however, conflicting evidence is also present. By using data from 7143 middle-aged and elderly humans (45-75 years) who participated in the Swedish EpiHealth cohort study, the present analysis sought to investigate whether self-reported shift work history would be associated with performance on the trail making test (TMT). The TMT has been proposed to be a useful neuropsychological tool to evaluate humans' executive cognitive function, which is known to decrease with age. After adjustment for potential confounders (e.g., age, education, and sleep duration), it was observed that current and recent former shift workers (worked shifts during the past 5 years) performed worse on the TMT than nonshift workers. In contrast, performance on the TMT did not differ between past shift workers (off from shift work for more than 5 years) and nonshift workers. Collectively, our results indicate that shift work history is linked to poorer performance on the TMT in a cohort of middle-aged and elderly humans.</p>},
  author       = {Titova, Olga E. and Lindberg, Eva and Elmståhl, Sölve and Lind, Lars and Schiöth, Helgi B. and Benedict, Christian},
  issn         = {0197-4580},
  keyword      = {Cohort study,Shift work history,Trail making test},
  language     = {eng},
  month        = {09},
  pages        = {23--29},
  publisher    = {Elsevier},
  series       = {Neurobiology of Aging},
  title        = {Association between shift work history and performance on the trail making test in middle-aged and elderly humans : The EpiHealth study},
  url          = {http://dx.doi.org/10.1016/j.neurobiolaging.2016.05.007},
  volume       = {45},
  year         = {2016},
}