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Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women

Gerdhem, Paul LU ; Ivaska, Kaisa LU ; Isaksson, Anders; Pettersson, Kim; Vaananen, H. Kalervo; Obrant, Karl LU and Åkesson, Kristina LU (2007) In Journal of Bone and Mineral Research 22(1). p.127-134
Abstract
Homocysteine has been suggested to be a risk factor for fracture, but the causal relationship is not clear. In 996 women from the OPRA study, high homocysteine level was associated with high bone marker levels and low BMD at baseline. During a mean 7-year follow-up, high homocysteine level was associated with mortality, but no clear association to fracture risk existed.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
fracture, mortality, ultrasound, bone, BMD, vitamin B-12 folate, homocysteine, aging, population studies, bone metabolic markers
in
Journal of Bone and Mineral Research
volume
22
issue
1
pages
127 - 134
publisher
AMBMR
external identifiers
  • wos:000243056300015
  • scopus:33845919859
ISSN
1523-4681
DOI
10.1359/jbmr.061003
language
English
LU publication?
yes
id
060914a4-d274-49c9-91b0-a9d411a2d2ee (old id 681624)
date added to LUP
2007-12-11 21:11:52
date last changed
2017-10-01 03:34:53
@article{060914a4-d274-49c9-91b0-a9d411a2d2ee,
  abstract     = {Homocysteine has been suggested to be a risk factor for fracture, but the causal relationship is not clear. In 996 women from the OPRA study, high homocysteine level was associated with high bone marker levels and low BMD at baseline. During a mean 7-year follow-up, high homocysteine level was associated with mortality, but no clear association to fracture risk existed.},
  author       = {Gerdhem, Paul and Ivaska, Kaisa and Isaksson, Anders and Pettersson, Kim and Vaananen, H. Kalervo and Obrant, Karl and Åkesson, Kristina},
  issn         = {1523-4681},
  keyword      = {fracture,mortality,ultrasound,bone,BMD,vitamin B-12 folate,homocysteine,aging,population studies,bone metabolic markers},
  language     = {eng},
  number       = {1},
  pages        = {127--134},
  publisher    = {AMBMR},
  series       = {Journal of Bone and Mineral Research},
  title        = {Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women},
  url          = {http://dx.doi.org/10.1359/jbmr.061003},
  volume       = {22},
  year         = {2007},
}