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Reduced mortality for women with mammography-detected breast cancer in east Denmark and south Sweden

Christensen, L. H. ; Engholm, G. ; Cortes, R. ; Ceberg, J. ; Tange, U. ; Andersson, M. ; Bladström, Anna LU ; Mouridsen, H. T. ; Möller, Torgil LU and Storm, Hans (2006) In European Journal of Cancer 42(16). p.2773-2780
Abstract
The 5-year relative survival from breast cancer in Denmark is 10 percentage points lower than in Sweden. This difference has been demonstrated previously as being caused partly by more involved lymph nodes and larger tumours in Denmark. Sweden has had nationwide mammography-screening coverage since 1991, whereas this is still in its infancy in Denmark. In the search for an explanation for the remaining survival difference, patient delay was a likely candidate. This study compared patient delay and mammography-detection between two national regions. Data on patient delay and mammography were obtained from hospital records from 1989 and 1994, and analysed using Cox proportional hazard analysis of death within the first 5 years, with the... (More)
The 5-year relative survival from breast cancer in Denmark is 10 percentage points lower than in Sweden. This difference has been demonstrated previously as being caused partly by more involved lymph nodes and larger tumours in Denmark. Sweden has had nationwide mammography-screening coverage since 1991, whereas this is still in its infancy in Denmark. In the search for an explanation for the remaining survival difference, patient delay was a likely candidate. This study compared patient delay and mammography-detection between two national regions. Data on patient delay and mammography were obtained from hospital records from 1989 and 1994, and analysed using Cox proportional hazard analysis of death within the first 5 years, with the factors age, country, delay/mammography detection and established patho-anatomic variables. A comparison of patient delay and mammography detection in 1989 and 1994 showed more mammography-detected tumours in south Sweden and more women with long delay in east Denmark. Mammography detection, but not long patient delay, had a significant effect on the death hazard when adjusting for patho-anatomic risk factors. The hazard ratio was not eliminated in 1989, but in 1994, the hazard ratio between east Denmark and south Sweden was reduced from 1.3 to 1.1. In conclusion, patient delay did not appear to have any effect on 5-year survival when adjusting for patho-anatomic factors, but tumour detection by mammography affected survival favourably and partly explained the survival difference between east Denmark and south Sweden. (c) 2006 Elsevier Ltd. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
screening, patient delay, mammography, breast cancer survival
in
European Journal of Cancer
volume
42
issue
16
pages
2773 - 2780
publisher
IFAC & Elsevier Ltd.
external identifiers
  • wos:000242501700026
  • scopus:33750036128
ISSN
1879-0852
DOI
10.1016/j.ejca.2006.03.036
language
English
LU publication?
yes
id
87efeb7d-14ef-4c79-bf96-b14976ac8c2c (old id 685233)
date added to LUP
2016-04-01 11:53:40
date last changed
2019-02-20 03:57:51
@article{87efeb7d-14ef-4c79-bf96-b14976ac8c2c,
  abstract     = {The 5-year relative survival from breast cancer in Denmark is 10 percentage points lower than in Sweden. This difference has been demonstrated previously as being caused partly by more involved lymph nodes and larger tumours in Denmark. Sweden has had nationwide mammography-screening coverage since 1991, whereas this is still in its infancy in Denmark. In the search for an explanation for the remaining survival difference, patient delay was a likely candidate. This study compared patient delay and mammography-detection between two national regions. Data on patient delay and mammography were obtained from hospital records from 1989 and 1994, and analysed using Cox proportional hazard analysis of death within the first 5 years, with the factors age, country, delay/mammography detection and established patho-anatomic variables. A comparison of patient delay and mammography detection in 1989 and 1994 showed more mammography-detected tumours in south Sweden and more women with long delay in east Denmark. Mammography detection, but not long patient delay, had a significant effect on the death hazard when adjusting for patho-anatomic risk factors. The hazard ratio was not eliminated in 1989, but in 1994, the hazard ratio between east Denmark and south Sweden was reduced from 1.3 to 1.1. In conclusion, patient delay did not appear to have any effect on 5-year survival when adjusting for patho-anatomic factors, but tumour detection by mammography affected survival favourably and partly explained the survival difference between east Denmark and south Sweden. (c) 2006 Elsevier Ltd. All rights reserved.},
  author       = {Christensen, L. H. and Engholm, G. and Cortes, R. and Ceberg, J. and Tange, U. and Andersson, M. and Bladström, Anna and Mouridsen, H. T. and Möller, Torgil and Storm, Hans},
  issn         = {1879-0852},
  language     = {eng},
  number       = {16},
  pages        = {2773--2780},
  publisher    = {IFAC & Elsevier Ltd.},
  series       = {European Journal of Cancer},
  title        = {Reduced mortality for women with mammography-detected breast cancer in east Denmark and south Sweden},
  url          = {http://dx.doi.org/10.1016/j.ejca.2006.03.036},
  doi          = {10.1016/j.ejca.2006.03.036},
  volume       = {42},
  year         = {2006},
}