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Outcomes of preterm children according to type of delivery onset: a nationwide population-based study

Morken, Nils-Halvdan; Källén, Karin LU and Jacobsson, Bo (2007) In Paediatric and Perinatal Epidemiology 21(5). p.458-464
Abstract
The objective of the study was to investigate whether spontaneous and iatrogenic preterm births are associated with different paediatric outcomes. A nationwide population-based study comprising 1 010 487 singletons used data from 1991 to 2001 from the Swedish Medical Birth Register and the Swedish Hospital Discharge Register. Intrauterine fetal deaths, unknown type of delivery onset and congenital malformations were excluded. Neonatal, perinatal and long-term neurological outcomes were studied. Spontaneous preterm births were compared with iatrogenic preterm births. Odds ratios (OR) and hazard ratios (HR) for outcome variables were obtained using the Mantel-Haenszel technique and Cox analyses respectively. Adjustments were made for... (More)
The objective of the study was to investigate whether spontaneous and iatrogenic preterm births are associated with different paediatric outcomes. A nationwide population-based study comprising 1 010 487 singletons used data from 1991 to 2001 from the Swedish Medical Birth Register and the Swedish Hospital Discharge Register. Intrauterine fetal deaths, unknown type of delivery onset and congenital malformations were excluded. Neonatal, perinatal and long-term neurological outcomes were studied. Spontaneous preterm births were compared with iatrogenic preterm births. Odds ratios (OR) and hazard ratios (HR) for outcome variables were obtained using the Mantel-Haenszel technique and Cox analyses respectively. Adjustments were made for gestational age at birth, maternal age, parity and smoking. The preterm population consisted of 34 215 (73.2%) spontaneous preterm infants and 12 511 (26.8%) iatrogenic preterm infants. Spontaneous preterm infants were at increased risk of cerebral palsy at gestational age 28-31 weeks (HR: 1.86 [95% CI: 1.12, 3.10]), and of sepsis at gestational age 32-33 weeks (HR: 1.58 [95% CI: 1.28, 1.96]). Other outcome variables were associated with iatrogenic preterm birth, especially respiratory and gastrointestinal diagnoses. In conclusion, spontaneous preterm birth and iatrogenic preterm birth are associated with different paediatric outcomes. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
respiratory distress syndrome, neonatal sepsis, gestational age, cerebral palsy, infant mortality, preterm delivery, onset of labour
in
Paediatric and Perinatal Epidemiology
volume
21
issue
5
pages
458 - 464
publisher
Wiley-Blackwell
external identifiers
  • wos:000249196700009
  • scopus:34547886860
ISSN
0269-5022
DOI
10.1111/j.1365-3016.2007.00823.x
language
English
LU publication?
yes
id
3ff44b12-9b4f-449b-9b69-16e2ff6368d4 (old id 688763)
date added to LUP
2007-12-13 15:52:49
date last changed
2017-10-29 03:31:36
@article{3ff44b12-9b4f-449b-9b69-16e2ff6368d4,
  abstract     = {The objective of the study was to investigate whether spontaneous and iatrogenic preterm births are associated with different paediatric outcomes. A nationwide population-based study comprising 1 010 487 singletons used data from 1991 to 2001 from the Swedish Medical Birth Register and the Swedish Hospital Discharge Register. Intrauterine fetal deaths, unknown type of delivery onset and congenital malformations were excluded. Neonatal, perinatal and long-term neurological outcomes were studied. Spontaneous preterm births were compared with iatrogenic preterm births. Odds ratios (OR) and hazard ratios (HR) for outcome variables were obtained using the Mantel-Haenszel technique and Cox analyses respectively. Adjustments were made for gestational age at birth, maternal age, parity and smoking. The preterm population consisted of 34 215 (73.2%) spontaneous preterm infants and 12 511 (26.8%) iatrogenic preterm infants. Spontaneous preterm infants were at increased risk of cerebral palsy at gestational age 28-31 weeks (HR: 1.86 [95% CI: 1.12, 3.10]), and of sepsis at gestational age 32-33 weeks (HR: 1.58 [95% CI: 1.28, 1.96]). Other outcome variables were associated with iatrogenic preterm birth, especially respiratory and gastrointestinal diagnoses. In conclusion, spontaneous preterm birth and iatrogenic preterm birth are associated with different paediatric outcomes.},
  author       = {Morken, Nils-Halvdan and Källén, Karin and Jacobsson, Bo},
  issn         = {0269-5022},
  keyword      = {respiratory distress syndrome,neonatal sepsis,gestational age,cerebral palsy,infant mortality,preterm delivery,onset of labour},
  language     = {eng},
  number       = {5},
  pages        = {458--464},
  publisher    = {Wiley-Blackwell},
  series       = {Paediatric and Perinatal Epidemiology},
  title        = {Outcomes of preterm children according to type of delivery onset: a nationwide population-based study},
  url          = {http://dx.doi.org/10.1111/j.1365-3016.2007.00823.x},
  volume       = {21},
  year         = {2007},
}