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Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

Gillberg, Linn ; Perfilyev, Alexander LU orcid ; Brøns, Charlotte ; Thomasen, Martin ; Grunnet, Louise G ; Volkov, Petr LU ; Rosqvist, Fredrik ; Iggman, David ; Dahlman, Ingrid and Risérus, Ulf , et al. (2016) In Diabetologia 59(4). p.799-812
Abstract
Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetologia
volume
59
issue
4
pages
799 - 812
publisher
Springer
external identifiers
  • pmid:26750116
  • scopus:84959547501
  • wos:000371802700018
  • pmid:26750116
ISSN
1432-0428
DOI
10.1007/s00125-015-3852-9
language
English
LU publication?
yes
id
68fb1fba-7708-460e-b2b5-6b601fedf1c3 (old id 8592468)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26750116?dopt=Abstract
date added to LUP
2016-04-04 07:59:24
date last changed
2022-04-23 08:55:58
@article{68fb1fba-7708-460e-b2b5-6b601fedf1c3,
  abstract     = {{Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.}},
  author       = {{Gillberg, Linn and Perfilyev, Alexander and Brøns, Charlotte and Thomasen, Martin and Grunnet, Louise G and Volkov, Petr and Rosqvist, Fredrik and Iggman, David and Dahlman, Ingrid and Risérus, Ulf and Rönn, Tina and Nilsson, Emma A and Vaag, Allan and Ling, Charlotte}},
  issn         = {{1432-0428}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{4}},
  pages        = {{799--812}},
  publisher    = {{Springer}},
  series       = {{Diabetologia}},
  title        = {{Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.}},
  url          = {{http://dx.doi.org/10.1007/s00125-015-3852-9}},
  doi          = {{10.1007/s00125-015-3852-9}},
  volume       = {{59}},
  year         = {{2016}},
}