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Age, parasites, and condition affect humoral immune response in tropical pythons

Ujvari, Beata LU and Madsen, Thomas LU (2006) In Behavioral Ecology 17(1). p.20-24
Abstract
Mounting an immune response has been suggested to be physiologically costly because of metabolic requirements of immune cells specifically and upregulation of the immune system in general. We investigated such costs in free-living water pythons (Liasis fuscus), immunized with a harmless antigen, keyhole limpet hemocyanin. In the present study, we analyze the independent effects of age, blood parasite load, and body condition on the ability to mount a humoral immune response (level of antibody production to novel antigens). Python humoral immune response decreased with increasing body length/age, decreased with increasing blood parasite load, and decreased with declining body condition. The results suggest an energetic trade-off between... (More)
Mounting an immune response has been suggested to be physiologically costly because of metabolic requirements of immune cells specifically and upregulation of the immune system in general. We investigated such costs in free-living water pythons (Liasis fuscus), immunized with a harmless antigen, keyhole limpet hemocyanin. In the present study, we analyze the independent effects of age, blood parasite load, and body condition on the ability to mount a humoral immune response (level of antibody production to novel antigens). Python humoral immune response decreased with increasing body length/age, decreased with increasing blood parasite load, and decreased with declining body condition. The results suggest an energetic trade-off between immunocompetence and other energetically costly processes. (Less)
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
humoral immune response, python, parasites, age, condition
in
Behavioral Ecology
volume
17
issue
1
pages
20 - 24
publisher
Oxford University Press
external identifiers
  • wos:000233489900004
  • scopus:28544441767
ISSN
1045-2249
DOI
10.1093/beheco/ari091
language
English
LU publication?
yes
id
a3690e36-4ff8-48da-8103-cbe76b28e1b8 (old id 693915)
date added to LUP
2016-04-01 16:02:19
date last changed
2021-09-01 03:16:19
@article{a3690e36-4ff8-48da-8103-cbe76b28e1b8,
  abstract     = {Mounting an immune response has been suggested to be physiologically costly because of metabolic requirements of immune cells specifically and upregulation of the immune system in general. We investigated such costs in free-living water pythons (Liasis fuscus), immunized with a harmless antigen, keyhole limpet hemocyanin. In the present study, we analyze the independent effects of age, blood parasite load, and body condition on the ability to mount a humoral immune response (level of antibody production to novel antigens). Python humoral immune response decreased with increasing body length/age, decreased with increasing blood parasite load, and decreased with declining body condition. The results suggest an energetic trade-off between immunocompetence and other energetically costly processes.},
  author       = {Ujvari, Beata and Madsen, Thomas},
  issn         = {1045-2249},
  language     = {eng},
  number       = {1},
  pages        = {20--24},
  publisher    = {Oxford University Press},
  series       = {Behavioral Ecology},
  title        = {Age, parasites, and condition affect humoral immune response in tropical pythons},
  url          = {http://dx.doi.org/10.1093/beheco/ari091},
  doi          = {10.1093/beheco/ari091},
  volume       = {17},
  year         = {2006},
}