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Intensive care after cardiac arrest

Hassager, Christian ; Meyer, Martin A.S. ; Perman, Sarah M. ; Møller, Jacob E. ; Kjaergaard, Jesper ; Nielsen, Niklas LU orcid ; Beske, Rasmus P. ; Horn, Jannike ; Lilja, Gisela LU and Skrifvars, Markus (2026) In European Heart Journal: Acute Cardiovascular Care 15(1). p.74-85
Abstract

Cardiac arrest causes an abrupt cessation of circulation, which rapidly leads to global ischaemia and hypoxia. Immediate and competent care is vital, and even when the circulation has been restored, there is a profound risk of patients never regaining consciousness due to hypoxic–ischaemic brain injury, or death due recurrent cardiac arrest or multiorgan failure. The complex pattern of symptoms seen in resuscitated cardiac arrest patients has been termed post-cardiac arrest syndrome and encompasses brain injury, myocardial dysfunction, systemic ischaemia and reperfusion response, and the pathological process that caused the cardiac arrest. This educational review describes the intensive care for resuscitated cardiac arrest patients and... (More)

Cardiac arrest causes an abrupt cessation of circulation, which rapidly leads to global ischaemia and hypoxia. Immediate and competent care is vital, and even when the circulation has been restored, there is a profound risk of patients never regaining consciousness due to hypoxic–ischaemic brain injury, or death due recurrent cardiac arrest or multiorgan failure. The complex pattern of symptoms seen in resuscitated cardiac arrest patients has been termed post-cardiac arrest syndrome and encompasses brain injury, myocardial dysfunction, systemic ischaemia and reperfusion response, and the pathological process that caused the cardiac arrest. This educational review describes the intensive care for resuscitated cardiac arrest patients and provides discussions of current evidence and emerging trends for key therapeutic areas.

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author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cardiac arrest, Haemodynamic goals, Neuroprognostication, Rehabilitation, Resuscitation, Revascularization, Seizures, Temperature control
in
European Heart Journal: Acute Cardiovascular Care
volume
15
issue
1
pages
12 pages
publisher
Oxford University Press
external identifiers
  • scopus:105033120624
  • pmid:40972086
ISSN
2048-8726
DOI
10.1093/ehjacc/zuaf119
language
English
LU publication?
yes
additional info
Publisher Copyright: © The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved.
id
69977e3d-f981-4f5c-979c-ee77c7c92628
date added to LUP
2026-05-05 16:48:05
date last changed
2026-06-02 18:43:51
@article{69977e3d-f981-4f5c-979c-ee77c7c92628,
  abstract     = {{<p>Cardiac arrest causes an abrupt cessation of circulation, which rapidly leads to global ischaemia and hypoxia. Immediate and competent care is vital, and even when the circulation has been restored, there is a profound risk of patients never regaining consciousness due to hypoxic–ischaemic brain injury, or death due recurrent cardiac arrest or multiorgan failure. The complex pattern of symptoms seen in resuscitated cardiac arrest patients has been termed post-cardiac arrest syndrome and encompasses brain injury, myocardial dysfunction, systemic ischaemia and reperfusion response, and the pathological process that caused the cardiac arrest. This educational review describes the intensive care for resuscitated cardiac arrest patients and provides discussions of current evidence and emerging trends for key therapeutic areas.</p>}},
  author       = {{Hassager, Christian and Meyer, Martin A.S. and Perman, Sarah M. and Møller, Jacob E. and Kjaergaard, Jesper and Nielsen, Niklas and Beske, Rasmus P. and Horn, Jannike and Lilja, Gisela and Skrifvars, Markus}},
  issn         = {{2048-8726}},
  keywords     = {{Cardiac arrest; Haemodynamic goals; Neuroprognostication; Rehabilitation; Resuscitation; Revascularization; Seizures; Temperature control}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{1}},
  pages        = {{74--85}},
  publisher    = {{Oxford University Press}},
  series       = {{European Heart Journal: Acute Cardiovascular Care}},
  title        = {{Intensive care after cardiac arrest}},
  url          = {{http://dx.doi.org/10.1093/ehjacc/zuaf119}},
  doi          = {{10.1093/ehjacc/zuaf119}},
  volume       = {{15}},
  year         = {{2026}},
}