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Microscopic Colitis is Associated with Several Concomitant Diseases.

Roth, Bodil LU ; Manjer, Jonas LU and Ohlsson, Bodil LU (2013) In Drug Target Insights 7. p.19-25
Abstract
Microscopic colitis (MC) is a disease with intestinal mucosal inflammation causing diarrhea, affecting predominantly middle-aged women. The etiology is unknown, but increased prevalence of autoimmune diseases in these patients has been described, although not compared with controls or adjusted for confounding factors. The aim of this study was to examine the prevalence of common diseases in patients with MC and controls from the general population. Hypertension, rheumatoid arthritis, asthma or bronchitis, ischemia, and diabetes mellitus were more prevalent in patients than in controls. The prevalence of gastric ulcer and cancer did not differ between the groups. Besides corticosteroids, many patients were also being treated with proton... (More)
Microscopic colitis (MC) is a disease with intestinal mucosal inflammation causing diarrhea, affecting predominantly middle-aged women. The etiology is unknown, but increased prevalence of autoimmune diseases in these patients has been described, although not compared with controls or adjusted for confounding factors. The aim of this study was to examine the prevalence of common diseases in patients with MC and controls from the general population. Hypertension, rheumatoid arthritis, asthma or bronchitis, ischemia, and diabetes mellitus were more prevalent in patients than in controls. The prevalence of gastric ulcer and cancer did not differ between the groups. Besides corticosteroids, many patients were also being treated with proton pump inhibitors, antidepressant drugs, angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists, statins, thyroid hormones, and beta-blockers. More patients than controls were former or current smokers (72.5% versus 57.7%). Thus, MC patients have an increased prevalence of several diseases, not only of autoimmune origin. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Drug Target Insights
volume
7
pages
19 - 25
publisher
Libertas Academica
external identifiers
  • pmid:24003301
  • scopus:84881492967
ISSN
1177-3928
DOI
10.4137/DTI.S12109
language
English
LU publication?
yes
id
6d04877b-a6b4-4e7b-8bf7-7087c0a88fa9 (old id 4066305)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24003301?dopt=Abstract
date added to LUP
2013-10-01 10:34:03
date last changed
2019-08-14 01:58:35
@article{6d04877b-a6b4-4e7b-8bf7-7087c0a88fa9,
  abstract     = {Microscopic colitis (MC) is a disease with intestinal mucosal inflammation causing diarrhea, affecting predominantly middle-aged women. The etiology is unknown, but increased prevalence of autoimmune diseases in these patients has been described, although not compared with controls or adjusted for confounding factors. The aim of this study was to examine the prevalence of common diseases in patients with MC and controls from the general population. Hypertension, rheumatoid arthritis, asthma or bronchitis, ischemia, and diabetes mellitus were more prevalent in patients than in controls. The prevalence of gastric ulcer and cancer did not differ between the groups. Besides corticosteroids, many patients were also being treated with proton pump inhibitors, antidepressant drugs, angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists, statins, thyroid hormones, and beta-blockers. More patients than controls were former or current smokers (72.5% versus 57.7%). Thus, MC patients have an increased prevalence of several diseases, not only of autoimmune origin.},
  author       = {Roth, Bodil and Manjer, Jonas and Ohlsson, Bodil},
  issn         = {1177-3928},
  language     = {eng},
  pages        = {19--25},
  publisher    = {Libertas Academica},
  series       = {Drug Target Insights},
  title        = {Microscopic Colitis is Associated with Several Concomitant Diseases.},
  url          = {http://dx.doi.org/10.4137/DTI.S12109},
  volume       = {7},
  year         = {2013},
}