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Diet quality scores and prediction of all-cause, cardiovascular and cancer mortality in a pan-european cohort study

Lassale, Camille ; Gunter, Marc J. ; Romaguera, Dora ; Peelen, Linda M. ; Van Der Schouw, Yvonne T. ; Beulens, Joline W J ; Freisling, Heinz ; Muller, David C. ; Ferrari, Pietro and Huybrechts, Inge , et al. (2016) In PLoS ONE 11(7).
Abstract

Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity... (More)

Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
11
issue
7
article number
e0159025
publisher
Public Library of Science (PLoS)
external identifiers
  • pmid:27409582
  • wos:000379508300050
  • scopus:84978771288
ISSN
1932-6203
DOI
10.1371/journal.pone.0159025
language
English
LU publication?
yes
id
6fb9c74d-01ec-42a3-a965-a658b6513d6e
date added to LUP
2016-08-02 10:43:22
date last changed
2025-03-08 13:55:00
@article{6fb9c74d-01ec-42a3-a965-a658b6513d6e,
  abstract     = {{<p>Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors.</p>}},
  author       = {{Lassale, Camille and Gunter, Marc J. and Romaguera, Dora and Peelen, Linda M. and Van Der Schouw, Yvonne T. and Beulens, Joline W J and Freisling, Heinz and Muller, David C. and Ferrari, Pietro and Huybrechts, Inge and Fagherazzi, Guy and Boutron-Ruault, Marie Christine and Affret, Aurélie and Overvad, Kim and Dahm, Christina C. and Olsen, Anja and Roswall, Nina and Tsilidis, Konstantinos K. and Katzke, Verena A. and Kühn, Tilman and Buijsse, Brian and Quirós, José Ramón and Sánchez-Cantalejo, Emilio and Etxezarreta, Nerea and Huerta, José María and Barricarte, Aurelio and Bonet, Catalina and Khaw, Kay Tee and Key, Timothy J. and Trichopoulou, Antonia and Bamia, Christina and Lagiou, Pagona and Palli, Domenico and Agnoli, Claudia and Tumino, Rosario and Fasanelli, Francesca and Panico, Salvatore and Bueno-de-Mesquita, H. Bas and Boer, Jolanda M A and Sonestedt, Emily and Nilsson, Lena Maria and Renström, Frida and Weiderpass, Elisabete and Skeie, Guri and Lund, Eiliv and Moons, Karel G M and Riboli, Elio and Tzoulaki, Ioanna}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  month        = {{07}},
  number       = {{7}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{Diet quality scores and prediction of all-cause, cardiovascular and cancer mortality in a pan-european cohort study}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0159025}},
  doi          = {{10.1371/journal.pone.0159025}},
  volume       = {{11}},
  year         = {{2016}},
}