Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial.
Feldt, Maria LU ; Bjarnadottir, Olöf LU ; Kimbung, Siker LU ; Jirström, Karin LU
; Bendahl, Pär-Ola
LU
; Veerla, Srinivas
LU
; Grabau, Dorthe
LU
; Hedenfalk, Ingrid
LU
and Borgquist, Signe
LU
(2015)
In Journal of Translational Medicine
13(133).
- Abstract
- Cholesterol lowering statins have been demonstrated to exert anti-tumoral effects on breast cancer by decreasing proliferation as measured by Ki67. The biological mechanisms behind the anti-proliferative effects remain elusive. The aim of this study was to investigate potential statin-induced effects on the central cell cycle regulators cyclin D1 and p27.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5461793
- author
- Feldt, Maria
LU
; Bjarnadottir, Olöf
LU
; Kimbung, Siker
LU
; Jirström, Karin
LU
; Bendahl, Pär-Ola
LU
; Veerla, Srinivas
LU
; Grabau, Dorthe
LU
; Hedenfalk, Ingrid
LU
and Borgquist, Signe
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Translational Medicine
- volume
- 13
- issue
- 133
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:25925673
- scopus:84928896902
- wos:000369795500001
- pmid:25925673
- ISSN
- 1479-5876
- DOI
- 10.1186/s12967-015-0486-0
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pathology, (Lund) (013030000), Oncology, MV (013035000)
- id
- 713ecc16-f543-48d0-9172-07c1bdc95ac0 (old id 5461793)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25925673?dopt=Abstract
- date added to LUP
- 2016-04-01 14:21:37
- date last changed
- 2024-02-25 13:45:45
@article{713ecc16-f543-48d0-9172-07c1bdc95ac0,
abstract = {{Cholesterol lowering statins have been demonstrated to exert anti-tumoral effects on breast cancer by decreasing proliferation as measured by Ki67. The biological mechanisms behind the anti-proliferative effects remain elusive. The aim of this study was to investigate potential statin-induced effects on the central cell cycle regulators cyclin D1 and p27.}},
author = {{Feldt, Maria and Bjarnadottir, Olöf and Kimbung, Siker and Jirström, Karin and Bendahl, Pär-Ola and Veerla, Srinivas and Grabau, Dorthe and Hedenfalk, Ingrid and Borgquist, Signe}},
issn = {{1479-5876}},
language = {{eng}},
number = {{133}},
publisher = {{BioMed Central (BMC)}},
series = {{Journal of Translational Medicine}},
title = {{Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial.}},
url = {{https://lup.lub.lu.se/search/files/3933109/8411605}},
doi = {{10.1186/s12967-015-0486-0}},
volume = {{13}},
year = {{2015}},
}