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Blood culture time to positivity in non-β-hemolytic streptococcal bacteremia as a predictor of infective endocarditis-a retrospective cohort study

Krus, David ; Kahn, Fredrik LU ; Nilson, Bo LU orcid ; Sunnerhagen, Torgny LU orcid and Rasmussen, Magnus LU (2022) In European Journal of Clinical Microbiology and Infectious Diseases 41(2). p.325-329
Abstract

Non-β-hemolytic streptococci (NBHS) cause infective endocarditis (IE) and a short blood culture time to positivity (TTP) is associated with risk of IE in bacteremia with other pathogens. In this retrospective population-based cohort study, we investigate if TTP is associated to IE or mortality. Of 263 episodes with NBHS bacteremia, 28 represented IE and the median TTP did not differ significantly between episodes with IE (15 h) and non-IE (15 h) (p=0.51). TTP was similar among those who survived and those who died within 30 days. However, TTP significantly differed when comparing the different streptococcal groups (p<0.001).

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Clinical Microbiology and Infectious Diseases
volume
41
issue
2
pages
325 - 329
publisher
Springer
external identifiers
  • pmid:34654986
  • scopus:85117091114
ISSN
0934-9723
DOI
10.1007/s10096-021-04339-7
language
English
LU publication?
yes
additional info
© 2021. The Author(s).
id
715d6775-380c-45b7-be58-fcc0b70a69e2
date added to LUP
2021-10-22 09:44:49
date last changed
2024-06-15 18:46:34
@article{715d6775-380c-45b7-be58-fcc0b70a69e2,
  abstract     = {{<p>Non-β-hemolytic streptococci (NBHS) cause infective endocarditis (IE) and a short blood culture time to positivity (TTP) is associated with risk of IE in bacteremia with other pathogens. In this retrospective population-based cohort study, we investigate if TTP is associated to IE or mortality. Of 263 episodes with NBHS bacteremia, 28 represented IE and the median TTP did not differ significantly between episodes with IE (15 h) and non-IE (15 h) (p=0.51). TTP was similar among those who survived and those who died within 30 days. However, TTP significantly differed when comparing the different streptococcal groups (p&lt;0.001).</p>}},
  author       = {{Krus, David and Kahn, Fredrik and Nilson, Bo and Sunnerhagen, Torgny and Rasmussen, Magnus}},
  issn         = {{0934-9723}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{325--329}},
  publisher    = {{Springer}},
  series       = {{European Journal of Clinical Microbiology and Infectious Diseases}},
  title        = {{Blood culture time to positivity in non-β-hemolytic streptococcal bacteremia as a predictor of infective endocarditis-a retrospective cohort study}},
  url          = {{https://lup.lub.lu.se/search/files/119180126/Blood_culture_time_to_positivity_in_non_hemolytic_streptococcal_bacteremia_as_a_predictor_of_infective_endocarditis.pdf}},
  doi          = {{10.1007/s10096-021-04339-7}},
  volume       = {{41}},
  year         = {{2022}},
}