Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Sources of Parent-Child Transmission of Drug Abuse : Path Analyses of Not-Lived-With Parental, Stepparental, Triparental, and Adoptive Families

Kendler, Kenneth S. LU ; Ohlsson, Henrik LU ; Sundquist, Kristina LU and Sundquist, Jan LU (2018) In Journal of Nervous and Mental Disease 206(4). p.239-244
Abstract

To clarify the origins of parent-child resemblance for drug abuse (DA), using national Swedish data, we fit path models to information on DA in parents and children from six informative family types: i) not-lived-with father, ii) not-lived-with mother, iii) stepfather, iv) stepmother, v) triparental, and vi) adoptive. From these families, we estimated parent-offspring resemblance reflecting the effects of genes + rearing, genes only, and rearing only. The estimates of parent-offspring correlations were statistically homogenous across family types. The weighted estimate of the father-offspring correlation for DA for genes + rearing, genes-only, and rearing-only relationships were, respectively, +0.26, +0.19, and +0.06. Parallel figures... (More)

To clarify the origins of parent-child resemblance for drug abuse (DA), using national Swedish data, we fit path models to information on DA in parents and children from six informative family types: i) not-lived-with father, ii) not-lived-with mother, iii) stepfather, iv) stepmother, v) triparental, and vi) adoptive. From these families, we estimated parent-offspring resemblance reflecting the effects of genes + rearing, genes only, and rearing only. The estimates of parent-offspring correlations were statistically homogenous across family types. The weighted estimate of the father-offspring correlation for DA for genes + rearing, genes-only, and rearing-only relationships were, respectively, +0.26, +0.19, and +0.06. Parallel figures for mother-offspring relationships were +0.19, +0.13, and +0.09. In both genes + rearing and genes-only parent-offspring relationships, DA correlations were stronger for fathers than for mothers. Both genetic and environmental factors contribute substantially to parent-offspring resemblance for DA and seem to be additive.

(Less)
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Drug abuse, environment, genetics, parent-offspring, rearing, Sweden
in
Journal of Nervous and Mental Disease
volume
206
issue
4
pages
6 pages
publisher
Wolters Kluwer
external identifiers
  • scopus:85045440027
  • pmid:29252928
ISSN
0022-3018
DOI
10.1097/NMD.0000000000000775
language
English
LU publication?
yes
id
7375ffa1-7e88-4dd6-a51e-0856ff63ecc6
date added to LUP
2018-04-25 16:25:12
date last changed
2021-10-06 02:09:30
@article{7375ffa1-7e88-4dd6-a51e-0856ff63ecc6,
  abstract     = {<p>To clarify the origins of parent-child resemblance for drug abuse (DA), using national Swedish data, we fit path models to information on DA in parents and children from six informative family types: i) not-lived-with father, ii) not-lived-with mother, iii) stepfather, iv) stepmother, v) triparental, and vi) adoptive. From these families, we estimated parent-offspring resemblance reflecting the effects of genes + rearing, genes only, and rearing only. The estimates of parent-offspring correlations were statistically homogenous across family types. The weighted estimate of the father-offspring correlation for DA for genes + rearing, genes-only, and rearing-only relationships were, respectively, +0.26, +0.19, and +0.06. Parallel figures for mother-offspring relationships were +0.19, +0.13, and +0.09. In both genes + rearing and genes-only parent-offspring relationships, DA correlations were stronger for fathers than for mothers. Both genetic and environmental factors contribute substantially to parent-offspring resemblance for DA and seem to be additive.</p>},
  author       = {Kendler, Kenneth S. and Ohlsson, Henrik and Sundquist, Kristina and Sundquist, Jan},
  issn         = {0022-3018},
  language     = {eng},
  month        = {04},
  number       = {4},
  pages        = {239--244},
  publisher    = {Wolters Kluwer},
  series       = {Journal of Nervous and Mental Disease},
  title        = {Sources of Parent-Child Transmission of Drug Abuse : Path Analyses of Not-Lived-With Parental, Stepparental, Triparental, and Adoptive Families},
  url          = {http://dx.doi.org/10.1097/NMD.0000000000000775},
  doi          = {10.1097/NMD.0000000000000775},
  volume       = {206},
  year         = {2018},
}