Biological Structures
(2017) In Experimental Methods in the Physical Sciences 49. p.1-75- Abstract
Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to... (More)
Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to macromolecular length scales-up to micrometers. The dynamics of biological molecules are described by Seydel in Chapter 2 of this thematic volume.
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- author
- Fisher, Zoe LU ; Jackson, Andrew LU ; Kovalevsky, Andrey ; Oksanen, Esko LU and Wacklin, Hanna LU
- organization
- publishing date
- 2017
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Crystallization, Deuteration, Macromolecular diffraction, Reflectometry, Small-angle neutron scattering
- host publication
- Experimental Methods in the Physical Sciences
- series title
- Experimental Methods in the Physical Sciences
- volume
- 49
- pages
- 75 pages
- publisher
- Academic Press
- external identifiers
-
- scopus:85024855675
- ISSN
- 10794042
- DOI
- 10.1016/B978-0-12-805324-9.00001-7
- language
- English
- LU publication?
- yes
- id
- 74e55ed2-d26e-425c-8103-24582ef0a530
- date added to LUP
- 2017-07-31 13:21:18
- date last changed
- 2022-04-01 18:36:19
@inbook{74e55ed2-d26e-425c-8103-24582ef0a530, abstract = {{<p>Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to macromolecular length scales-up to micrometers. The dynamics of biological molecules are described by Seydel in Chapter 2 of this thematic volume.</p>}}, author = {{Fisher, Zoe and Jackson, Andrew and Kovalevsky, Andrey and Oksanen, Esko and Wacklin, Hanna}}, booktitle = {{Experimental Methods in the Physical Sciences}}, issn = {{10794042}}, keywords = {{Crystallization; Deuteration; Macromolecular diffraction; Reflectometry; Small-angle neutron scattering}}, language = {{eng}}, pages = {{1--75}}, publisher = {{Academic Press}}, series = {{Experimental Methods in the Physical Sciences}}, title = {{Biological Structures}}, url = {{http://dx.doi.org/10.1016/B978-0-12-805324-9.00001-7}}, doi = {{10.1016/B978-0-12-805324-9.00001-7}}, volume = {{49}}, year = {{2017}}, }