Kernel-based Estimate of the Insulin Action of Rapid-Acting Insulin in Home-Monitored Data
Ståhl, Fredrik LU ; Lindström, Erik LU
; Landin-Olsson, Mona
LU
and Johansson, Rolf
LU
(2015)
In IFAC-PapersOnLine
48(28).
p.715-720
- Abstract
- To improve glycemic control in insulin-dependent diabetes, estimates of the glucose- lowering effect of insulin-the insulin action (IA)-and the dynamics thereof are essential. The current practice relies on generic estimates of the dynamic shape of the IA and rules-of-thumb to assess the total glucose-lowering effect. In this paper we present individualized estimates based on home-monitored data, incorporating a kernel-based estimate that also accounts for the nonlinear behavior of the IA across the glucose range. The method is successfully validated on 29 patients on continuous insulin pump therapy.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7662b5f2-86b0-4405-9f27-3367a3d50f8a
- author
- Ståhl, Fredrik
LU
; Lindström, Erik
LU
; Landin-Olsson, Mona
LU
and Johansson, Rolf
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- IFAC-PapersOnLine
- volume
- 48
- issue
- 28
- pages
- 6 pages
- publisher
- IFAC Secretariat
- external identifiers
-
- scopus:84988484495
- ISSN
- 2405-8963
- DOI
- 10.1016/j.ifacol.2015.12.214
- project
- DIAdvisor
- language
- English
- LU publication?
- yes
- id
- 7662b5f2-86b0-4405-9f27-3367a3d50f8a
- date added to LUP
- 2016-09-13 13:20:13
- date last changed
- 2024-10-04 05:18:44
@article{7662b5f2-86b0-4405-9f27-3367a3d50f8a,
abstract = {{To improve glycemic control in insulin-dependent diabetes, estimates of the glucose- lowering effect of insulin-the insulin action (IA)-and the dynamics thereof are essential. The current practice relies on generic estimates of the dynamic shape of the IA and rules-of-thumb to assess the total glucose-lowering effect. In this paper we present individualized estimates based on home-monitored data, incorporating a kernel-based estimate that also accounts for the nonlinear behavior of the IA across the glucose range. The method is successfully validated on 29 patients on continuous insulin pump therapy.}},
author = {{Ståhl, Fredrik and Lindström, Erik and Landin-Olsson, Mona and Johansson, Rolf}},
issn = {{2405-8963}},
language = {{eng}},
number = {{28}},
pages = {{715--720}},
publisher = {{IFAC Secretariat}},
series = {{IFAC-PapersOnLine}},
title = {{Kernel-based Estimate of the Insulin Action of Rapid-Acting Insulin in Home-Monitored Data}},
url = {{http://dx.doi.org/10.1016/j.ifacol.2015.12.214}},
doi = {{10.1016/j.ifacol.2015.12.214}},
volume = {{48}},
year = {{2015}},
}