Phthalate levels in prenatal and postnatal bedroom dust in the SELMA study
Preece, Anna Sofia ; Shu, Huan ; Knutz, Malin ; Krais, Annette M. LU
and Bornehag, Carl Gustaf
LU
(2022)
In Environmental Research
212(Part C).
- Abstract
Phthalates are common in polyvinyl chloride (PVC) plastics and numerous consumer goods in our homes from which they can migrate and adhere to indoor dust particles. It is known that indoor dust exposure contribute to human phthalate intake; however, there is a lack of large studies with a repeated-measure design investigating how phthalate levels in indoor dust may vary over time in people's homes. This study investigated levels of seven phthalates and one alternative plasticiser di-iso-nonyl-cyclohexane-di-carboxylate (DiNCH) in bedroom dust collected prenatally around week 25 during pregnancy and postnatally at six months after birth, from 496 Swedish homes. Prenatal and postnatal phthalate levels were compared using correlation and... (More)
Phthalates are common in polyvinyl chloride (PVC) plastics and numerous consumer goods in our homes from which they can migrate and adhere to indoor dust particles. It is known that indoor dust exposure contribute to human phthalate intake; however, there is a lack of large studies with a repeated-measure design investigating how phthalate levels in indoor dust may vary over time in people's homes. This study investigated levels of seven phthalates and one alternative plasticiser di-iso-nonyl-cyclohexane-di-carboxylate (DiNCH) in bedroom dust collected prenatally around week 25 during pregnancy and postnatally at six months after birth, from 496 Swedish homes. Prenatal and postnatal phthalate levels were compared using correlation and season-adjusted general linear regression models. Over the nine-month period, levels of six out of seven phthalates were associated as indicated by a positive Pearson correlation (0.18 < r < 0.50, P < .001) and Lin's concordance correlation between matched prenatal and postnatal dust samples. Compared to prenatal levels, the season-adjusted postnatal levels decreased for five phthalates, whilst di-ethyl-hexyl phthalate (DEHP), di-2-propylheptyl phthalate (DPHP) and DiNCH increased. The results suggest that families with higher phthalate levels in bedroom dust during pregnancy are likely to remain among those with higher levels in the infancy period. However, all average phthalate levels changed over this specific nine-month period suggesting that available phthalate sources or their use were altered between the dust collections. Changes in home characteristics, family lifestyle, and phthalate replacement trends may contribute to explain the differences.
(Less)
- author
- Preece, Anna Sofia
; Shu, Huan
; Knutz, Malin
; Krais, Annette M.
LU
and Bornehag, Carl Gustaf
LU
- organization
- publishing date
- 2022-09
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Child, Human exposure, Indoor dust, Infant, Plasticisers, Pregnancy
- in
- Environmental Research
- volume
- 212
- issue
- Part C
- article number
- 113429
- publisher
- Elsevier
- external identifiers
-
- scopus:85130153465
- pmid:35533715
- ISSN
- 0013-9351
- DOI
- 10.1016/j.envres.2022.113429
- language
- English
- LU publication?
- yes
- additional info
- Funding Information: This work was supported by The Swedish Asthma and Allergy Association's research foundation, the Swedish Research Council (FORMAS), the Swedish Foundation for Health Care Sciences and Allergy Research , and the County Council of Värmland . The authors also want to acknowledge the participants for their generous collaboration and the nurses and other staff whose assistance made the recruitment and data collection for this study possible. Publisher Copyright: © 2022 The Authors
- id
- 76b240f2-1e79-4e56-b635-93daefb9d238
- date added to LUP
- 2022-07-19 08:24:03
- date last changed
- 2024-06-11 07:15:16
@article{76b240f2-1e79-4e56-b635-93daefb9d238,
abstract = {{<p>Phthalates are common in polyvinyl chloride (PVC) plastics and numerous consumer goods in our homes from which they can migrate and adhere to indoor dust particles. It is known that indoor dust exposure contribute to human phthalate intake; however, there is a lack of large studies with a repeated-measure design investigating how phthalate levels in indoor dust may vary over time in people's homes. This study investigated levels of seven phthalates and one alternative plasticiser di-iso-nonyl-cyclohexane-di-carboxylate (DiNCH) in bedroom dust collected prenatally around week 25 during pregnancy and postnatally at six months after birth, from 496 Swedish homes. Prenatal and postnatal phthalate levels were compared using correlation and season-adjusted general linear regression models. Over the nine-month period, levels of six out of seven phthalates were associated as indicated by a positive Pearson correlation (0.18 < r < 0.50, P < .001) and Lin's concordance correlation between matched prenatal and postnatal dust samples. Compared to prenatal levels, the season-adjusted postnatal levels decreased for five phthalates, whilst di-ethyl-hexyl phthalate (DEHP), di-2-propylheptyl phthalate (DPHP) and DiNCH increased. The results suggest that families with higher phthalate levels in bedroom dust during pregnancy are likely to remain among those with higher levels in the infancy period. However, all average phthalate levels changed over this specific nine-month period suggesting that available phthalate sources or their use were altered between the dust collections. Changes in home characteristics, family lifestyle, and phthalate replacement trends may contribute to explain the differences.</p>}},
author = {{Preece, Anna Sofia and Shu, Huan and Knutz, Malin and Krais, Annette M. and Bornehag, Carl Gustaf}},
issn = {{0013-9351}},
keywords = {{Child; Human exposure; Indoor dust; Infant; Plasticisers; Pregnancy}},
language = {{eng}},
number = {{Part C}},
publisher = {{Elsevier}},
series = {{Environmental Research}},
title = {{Phthalate levels in prenatal and postnatal bedroom dust in the SELMA study}},
url = {{http://dx.doi.org/10.1016/j.envres.2022.113429}},
doi = {{10.1016/j.envres.2022.113429}},
volume = {{212}},
year = {{2022}},
}