Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly.
(2015) In Bone 79. p.105-109- Abstract
- ALOX12 and ALOX15 encode arachidonate lipoxygenases which produce lipid metabolites involved in inflammatory processes. Metabolites generated by ALOX12 and ALOX15 can activate the expression of the potent pro-inflammatory cytokine IL-6, and produce endogenous ligands for PPARG. In this study, polymorphisms in ALOX12, ALOX15, IL6 and PPARG were investigated for association with bone properties in young and elderly Swedish women.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7508486
- author
- Herlin, Maria LU ; McGuigan, Fiona LU ; Luthman, Holger LU and Åkesson, Kristina LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Bone
- volume
- 79
- pages
- 105 - 109
- publisher
- Elsevier
- external identifiers
-
- pmid:26036173
- wos:000359509700015
- scopus:84930945200
- pmid:26036173
- ISSN
- 1873-2763
- DOI
- 10.1016/j.bone.2015.05.035
- language
- English
- LU publication?
- yes
- id
- 76e52e2e-a51e-4757-a31f-d256ddf66e3e (old id 7508486)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26036173?dopt=Abstract
- date added to LUP
- 2016-04-01 10:26:49
- date last changed
- 2024-02-21 16:57:14
@article{76e52e2e-a51e-4757-a31f-d256ddf66e3e, abstract = {{ALOX12 and ALOX15 encode arachidonate lipoxygenases which produce lipid metabolites involved in inflammatory processes. Metabolites generated by ALOX12 and ALOX15 can activate the expression of the potent pro-inflammatory cytokine IL-6, and produce endogenous ligands for PPARG. In this study, polymorphisms in ALOX12, ALOX15, IL6 and PPARG were investigated for association with bone properties in young and elderly Swedish women.}}, author = {{Herlin, Maria and McGuigan, Fiona and Luthman, Holger and Åkesson, Kristina}}, issn = {{1873-2763}}, language = {{eng}}, pages = {{105--109}}, publisher = {{Elsevier}}, series = {{Bone}}, title = {{Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly.}}, url = {{https://lup.lub.lu.se/search/files/1852421/8565860.pdf}}, doi = {{10.1016/j.bone.2015.05.035}}, volume = {{79}}, year = {{2015}}, }