Advanced

Stem cell biomarker ALDH1A1 in breast cancer shows an association with prognosis and clinicopathological variables that is highly cut-off dependent.

Sjöström, Martin LU ; Werner Hartman, Linda LU ; Honeth, Gabriella LU ; Grabau, Dorthe LU ; Malmström, Per LU ; Hegardt, Cecilia LU ; Fernö, Mårten LU and Niméus, Emma LU (2015) In Journal of Clinical Pathology 68(12). p.1012-1019
Abstract
Aldehyde dehydrogenase family 1 member A1 (ALDH1A1) is a putative marker of breast cancer stem cells (CSCs) with prognostic implications when expressed in cancer or stroma. However, previous results are contradictory and we therefore aimed to further evaluate the impact of ALDH1A1 on distant disease-free survival (DDFS) and correlation with clinicopathological variables in breast cancer, specifically by evaluating different cut-offs.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Pathology
volume
68
issue
12
pages
1012 - 1019
publisher
BMJ Publishing Group
external identifiers
  • pmid:26175266
  • wos:000365340200009
  • scopus:84958180531
ISSN
1472-4146
DOI
10.1136/jclinpath-2015-203092
language
English
LU publication?
yes
id
35172bc6-2797-4032-8e99-52b56f39d87f (old id 7749569)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26175266?dopt=Abstract
date added to LUP
2015-08-08 19:42:49
date last changed
2017-10-01 03:14:11
@article{35172bc6-2797-4032-8e99-52b56f39d87f,
  abstract     = {Aldehyde dehydrogenase family 1 member A1 (ALDH1A1) is a putative marker of breast cancer stem cells (CSCs) with prognostic implications when expressed in cancer or stroma. However, previous results are contradictory and we therefore aimed to further evaluate the impact of ALDH1A1 on distant disease-free survival (DDFS) and correlation with clinicopathological variables in breast cancer, specifically by evaluating different cut-offs.},
  author       = {Sjöström, Martin and Werner Hartman, Linda and Honeth, Gabriella and Grabau, Dorthe and Malmström, Per and Hegardt, Cecilia and Fernö, Mårten and Niméus, Emma},
  issn         = {1472-4146},
  language     = {eng},
  number       = {12},
  pages        = {1012--1019},
  publisher    = {BMJ Publishing Group},
  series       = {Journal of Clinical Pathology},
  title        = {Stem cell biomarker ALDH1A1 in breast cancer shows an association with prognosis and clinicopathological variables that is highly cut-off dependent.},
  url          = {http://dx.doi.org/10.1136/jclinpath-2015-203092},
  volume       = {68},
  year         = {2015},
}