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Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing.

Alkner, Sara LU ; Tang, Man-Hung Eric LU ; Brueffer, Christian LU ; Dahlgren, Malin LU ; Chen, Yilun LU ; Olsson, Eleonor LU ; Winter, Christof LU ; Baker, Sara LU ; Ehinger, Anna LU and Rydén, Lisa LU , et al. (2015) In Breast Cancer Research 17(1).
Abstract
By convention, a contralateral breast cancer (CBC) is treated as a new primary tumor, independent of the first cancer (BC1). Although there have been indications that the second tumor (BC2) sometimes may represent a metastatic spread of BC1, this has never been conclusively shown. We sought to apply next-generation sequencing to determine a "genetic barcode" for each tumor and reveal the clonal relationship of CBCs.
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publication status
published
subject
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Breast Cancer Research
volume
17
issue
1
publisher
BioMed Central
external identifiers
  • pmid:26242876
  • wos:000359048900003
  • scopus:84938600532
ISSN
1465-5411
DOI
10.1186/s13058-015-0608-x
language
English
LU publication?
yes
id
ff497f36-c945-4031-9795-f1816964fb50 (old id 7844721)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26242876?dopt=Abstract
date added to LUP
2015-09-05 13:35:27
date last changed
2017-05-14 03:14:52
@article{ff497f36-c945-4031-9795-f1816964fb50,
  abstract     = {By convention, a contralateral breast cancer (CBC) is treated as a new primary tumor, independent of the first cancer (BC1). Although there have been indications that the second tumor (BC2) sometimes may represent a metastatic spread of BC1, this has never been conclusively shown. We sought to apply next-generation sequencing to determine a "genetic barcode" for each tumor and reveal the clonal relationship of CBCs.},
  articleno    = {102},
  author       = {Alkner, Sara and Tang, Man-Hung Eric and Brueffer, Christian and Dahlgren, Malin and Chen, Yilun and Olsson, Eleonor and Winter, Christof and Baker, Sara and Ehinger, Anna and Rydén, Lisa and Saal, Lao and Fernö, Mårten and Gruvberger, Sofia},
  issn         = {1465-5411},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Breast Cancer Research},
  title        = {Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing.},
  url          = {http://dx.doi.org/10.1186/s13058-015-0608-x},
  volume       = {17},
  year         = {2015},
}