Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing.
(2015) In Breast Cancer Research 17(1).- Abstract
- By convention, a contralateral breast cancer (CBC) is treated as a new primary tumor, independent of the first cancer (BC1). Although there have been indications that the second tumor (BC2) sometimes may represent a metastatic spread of BC1, this has never been conclusively shown. We sought to apply next-generation sequencing to determine a "genetic barcode" for each tumor and reveal the clonal relationship of CBCs.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7844721
- author
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Breast Cancer Research
- volume
- 17
- issue
- 1
- article number
- 102
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26242876
- wos:000359048900003
- scopus:84938600532
- pmid:26242876
- ISSN
- 1465-5411
- DOI
- 10.1186/s13058-015-0608-x
- language
- English
- LU publication?
- yes
- id
- ff497f36-c945-4031-9795-f1816964fb50 (old id 7844721)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26242876?dopt=Abstract
- date added to LUP
- 2016-04-01 10:40:47
- date last changed
- 2022-04-28 00:22:15
@article{ff497f36-c945-4031-9795-f1816964fb50, abstract = {{By convention, a contralateral breast cancer (CBC) is treated as a new primary tumor, independent of the first cancer (BC1). Although there have been indications that the second tumor (BC2) sometimes may represent a metastatic spread of BC1, this has never been conclusively shown. We sought to apply next-generation sequencing to determine a "genetic barcode" for each tumor and reveal the clonal relationship of CBCs.}}, author = {{Alkner, Sara and Tang, Man-Hung Eric and Brueffer, Christian and Dahlgren, Malin and Chen, Yilun and Olsson, Eleonor and Winter, Christof and Baker, Sara and Ehinger, Anna and Rydén, Lisa and Saal, Lao and Fernö, Mårten and Gruvberger, Sofia}}, issn = {{1465-5411}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{Breast Cancer Research}}, title = {{Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing.}}, url = {{https://lup.lub.lu.se/search/files/2047343/8619268}}, doi = {{10.1186/s13058-015-0608-x}}, volume = {{17}}, year = {{2015}}, }