Study of ATP-release from acoustically levitated eryhrocytes
(2007) Micro Total Analysis Systems 2007 2. p.1372-1374- Abstract
- Erythrocytes (red blood cells) are known to produce large amounts of Adenosine Triphosphate (ATP). It has recently become clear that the ATP-release is part of a mechanism controlling the dilation of the body’s blood vessels. The study of the erythrocyte’s behaviour is complicated by the fact that they respond easily to any physical contact. In this paper we propose a new method for studying the dynamics of the ATP-release by combining non-contact acoustic trapping in a microfluidic chip with a chemiluminiscent assay. Sensitivity levels down to 10 pM were achievable and the ATP-release from a cluster of levitated live erythrocytes was recorded.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/789975
- author
- Evander, Mikael LU ; Mileros, Karolina ; Högberg, Carl LU ; Erlinge, David LU ; Almqvist, Monica LU ; Laurell, Thomas LU and Nilsson, Johan LU
- organization
- publishing date
- 2007
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Chemiluminiscence, Erythrocytes, ATP, Acoustic trapping
- host publication
- The proceedings of micro total analysis systems 2007
- editor
- Viovy, Jean-Louis ; Tabeling, Patrick ; Descroix, Stephanie and Malaquin, Laurent
- volume
- 2
- pages
- 3 pages
- publisher
- Chemical and Biological Microsystems Society
- conference name
- Micro Total Analysis Systems 2007
- conference dates
- 2007-10-07 - 2007-10-11
- ISBN
- 978-0-9798064-0-7
- language
- English
- LU publication?
- yes
- id
- 74b8ec18-9981-446c-91ae-14bcf7343778 (old id 789975)
- date added to LUP
- 2016-04-04 11:46:09
- date last changed
- 2018-11-21 21:07:04
@inproceedings{74b8ec18-9981-446c-91ae-14bcf7343778, abstract = {{Erythrocytes (red blood cells) are known to produce large amounts of Adenosine Triphosphate (ATP). It has recently become clear that the ATP-release is part of a mechanism controlling the dilation of the body’s blood vessels. The study of the erythrocyte’s behaviour is complicated by the fact that they respond easily to any physical contact. In this paper we propose a new method for studying the dynamics of the ATP-release by combining non-contact acoustic trapping in a microfluidic chip with a chemiluminiscent assay. Sensitivity levels down to 10 pM were achievable and the ATP-release from a cluster of levitated live erythrocytes was recorded.}}, author = {{Evander, Mikael and Mileros, Karolina and Högberg, Carl and Erlinge, David and Almqvist, Monica and Laurell, Thomas and Nilsson, Johan}}, booktitle = {{The proceedings of micro total analysis systems 2007}}, editor = {{Viovy, Jean-Louis and Tabeling, Patrick and Descroix, Stephanie and Malaquin, Laurent}}, isbn = {{978-0-9798064-0-7}}, keywords = {{Chemiluminiscence; Erythrocytes; ATP; Acoustic trapping}}, language = {{eng}}, pages = {{1372--1374}}, publisher = {{Chemical and Biological Microsystems Society}}, title = {{Study of ATP-release from acoustically levitated eryhrocytes}}, volume = {{2}}, year = {{2007}}, }