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Study of ATP-release from acoustically levitated eryhrocytes

Evander, Mikael LU ; Mileros, Karolina; Högberg, Carl LU ; Erlinge, David LU ; Almqvist, Monica LU ; Laurell, Thomas LU and Nilsson, Johan LU (2007) Micro Total Analysis Systems 2007 In The proceedings of micro total analysis systems 2007 2. p.1372-1374
Abstract
Erythrocytes (red blood cells) are known to produce large amounts of Adenosine Triphosphate (ATP). It has recently become clear that the ATP-release is part of a mechanism controlling the dilation of the body’s blood vessels. The study of the erythrocyte’s behaviour is complicated by the fact that they respond easily to any physical contact. In this paper we propose a new method for studying the dynamics of the ATP-release by combining non-contact acoustic trapping in a microfluidic chip with a chemiluminiscent assay. Sensitivity levels down to 10 pM were achievable and the ATP-release from a cluster of levitated live erythrocytes was recorded.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Chemiluminiscence, Erythrocytes, ATP, Acoustic trapping
in
The proceedings of micro total analysis systems 2007
editor
Viovy, Jean-Louis; Tabeling, Patrick; Descroix, Stephanie; Malaquin, Laurent; ; ; and
volume
2
pages
3 pages
publisher
Chemical and Biological Microsystems Society
conference name
Micro Total Analysis Systems 2007
ISBN
978-0-9798064-0-7
language
English
LU publication?
yes
id
74b8ec18-9981-446c-91ae-14bcf7343778 (old id 789975)
date added to LUP
2007-12-21 10:53:15
date last changed
2016-10-07 16:52:20
@inproceedings{74b8ec18-9981-446c-91ae-14bcf7343778,
  abstract     = {Erythrocytes (red blood cells) are known to produce large amounts of Adenosine Triphosphate (ATP). It has recently become clear that the ATP-release is part of a mechanism controlling the dilation of the body’s blood vessels. The study of the erythrocyte’s behaviour is complicated by the fact that they respond easily to any physical contact. In this paper we propose a new method for studying the dynamics of the ATP-release by combining non-contact acoustic trapping in a microfluidic chip with a chemiluminiscent assay. Sensitivity levels down to 10 pM were achievable and the ATP-release from a cluster of levitated live erythrocytes was recorded.},
  author       = {Evander, Mikael and Mileros, Karolina and Högberg, Carl and Erlinge, David and Almqvist, Monica and Laurell, Thomas and Nilsson, Johan},
  booktitle    = {The proceedings of micro total analysis systems 2007},
  editor       = {Viovy, Jean-Louis and Tabeling, Patrick and Descroix, Stephanie and Malaquin, Laurent},
  isbn         = {978-0-9798064-0-7},
  keyword      = {Chemiluminiscence,Erythrocytes,ATP,Acoustic trapping},
  language     = {eng},
  pages        = {1372--1374},
  publisher    = {Chemical and Biological Microsystems Society},
  title        = {Study of ATP-release from acoustically levitated eryhrocytes},
  volume       = {2},
  year         = {2007},
}