Fruits and vegetables and renal cell carcinoma: Findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)
(2006) In International Journal of Cancer 118(12). p.3133-3139- Abstract
- We examined the association between fruits and vegetables and risk of renal cell carcinoma (RCC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Dietary intake data and complete follow-up information on cancer incidence were available for 375,851 participants recruited in EPIC centers of 8 countries. During an average follow-up of 6.2 years, 306 incident cases of RCC were identified. The associations of consumption of total vegetables, total fruits, combined total fruits and vegetables and specific subtypes of vegetables with RCC risk were analyzed using Cox proportional hazards, stratified by centre and adjusted for potential confounders. No significant associations between fruit and vegetable consumption and... (More)
- We examined the association between fruits and vegetables and risk of renal cell carcinoma (RCC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Dietary intake data and complete follow-up information on cancer incidence were available for 375,851 participants recruited in EPIC centers of 8 countries. During an average follow-up of 6.2 years, 306 incident cases of RCC were identified. The associations of consumption of total vegetables, total fruits, combined total fruits and vegetables and specific subtypes of vegetables with RCC risk were analyzed using Cox proportional hazards, stratified by centre and adjusted for potential confounders. No significant associations between fruit and vegetable consumption and RCC risk were observed despite a wide range of intake. The estimated relative risks (95% confidence intervals [CI]) in men and women combined were 0.97 (0.85-1.11) per 40 g increase in vegetable intake, 1.03 (0.97-1.08) per 40 g increase in fruit intake and 1.02 (0.93-1.11) per 80 g increase in fruit and vegetable intake combined. Among the vegetable subtypes, an inverse association was observed for root vegetables (RR per 8 g increase: 0.88; 95% CI: 0.78-0.99). These results suggest that total consumption of fruits and vegetables is not related to risk of RCC, although we cannot exclude the possibility that very low consumption is related to higher risk. The relationship of specific fruit and vegetable subgroups with RCC risk warrant further investigation. (Less)
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https://lup.lub.lu.se/record/409528
- author
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- incidence, food, cohort study, epidemiology, kidney cancer
- in
- International Journal of Cancer
- volume
- 118
- issue
- 12
- pages
- 3133 - 3139
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000237331600029
- pmid:16425278
- scopus:33646410103
- pmid:16425278
- ISSN
- 0020-7136
- DOI
- 10.1002/ijc.21765
- language
- English
- LU publication?
- yes
- id
- 7dbe0394-d287-4402-85b0-82643f913f88 (old id 409528)
- date added to LUP
- 2016-04-01 11:55:19
- date last changed
- 2022-03-28 17:39:15
@article{7dbe0394-d287-4402-85b0-82643f913f88,
abstract = {{We examined the association between fruits and vegetables and risk of renal cell carcinoma (RCC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Dietary intake data and complete follow-up information on cancer incidence were available for 375,851 participants recruited in EPIC centers of 8 countries. During an average follow-up of 6.2 years, 306 incident cases of RCC were identified. The associations of consumption of total vegetables, total fruits, combined total fruits and vegetables and specific subtypes of vegetables with RCC risk were analyzed using Cox proportional hazards, stratified by centre and adjusted for potential confounders. No significant associations between fruit and vegetable consumption and RCC risk were observed despite a wide range of intake. The estimated relative risks (95% confidence intervals [CI]) in men and women combined were 0.97 (0.85-1.11) per 40 g increase in vegetable intake, 1.03 (0.97-1.08) per 40 g increase in fruit intake and 1.02 (0.93-1.11) per 80 g increase in fruit and vegetable intake combined. Among the vegetable subtypes, an inverse association was observed for root vegetables (RR per 8 g increase: 0.88; 95% CI: 0.78-0.99). These results suggest that total consumption of fruits and vegetables is not related to risk of RCC, although we cannot exclude the possibility that very low consumption is related to higher risk. The relationship of specific fruit and vegetable subgroups with RCC risk warrant further investigation.}},
author = {{Weikert, S and Boeing, H and Pischon, T and Olsen, A and Tjonneland, A and Overvad, K and Becker, N and Linseisen, J and Lahmann, PH and Arvaniti, A and Kassapa, C and Trichoupoulou, A and Sieri, S and Palli, D and Tumino, R and Vineis, P and Panico, S and van Gils, CH and Peeters, PHM and Bueno-De-Mesquita, HB and Buchner, FL and Berglund, Göran and Wirfält, Elisabet and Ljungberg, B and Hallmans, G and Pera, G and Dorronsoro, M and Barricarte Gurrea, A and Navarro, C and Martinez, C and Quorós, J R and Allen, N and Roddam, A and Bingham, S and Jenab, M and Slimani, N and Norat, T and Riboli, E}},
issn = {{0020-7136}},
keywords = {{incidence; food; cohort study; epidemiology; kidney cancer}},
language = {{eng}},
number = {{12}},
pages = {{3133--3139}},
publisher = {{John Wiley & Sons Inc.}},
series = {{International Journal of Cancer}},
title = {{Fruits and vegetables and renal cell carcinoma: Findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)}},
url = {{http://dx.doi.org/10.1002/ijc.21765}},
doi = {{10.1002/ijc.21765}},
volume = {{118}},
year = {{2006}},
}