Are Purkinje Cell Pauses Drivers of Classically Conditioned Blink Responses?
(2016) In Cerebellum 15(4). p.526-534- Abstract
- Several lines of evidence show that classical or Pavlovian conditioning of blink responses depends on the cerebellum. Recordings from cerebellar Purkinje cells that control the eyelid and the conditioned blink show that during training with a conditioning protocol, a Purkinje cell develops a pause response to the conditional stimulus. This conditioned cellular response has many of the properties that characterise the overt blink. The present paper argues that the learned Purkinje cell pause response is the memory trace and main driver of the overt conditioned blink and that it explains many well-known behavioural phenomena.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8035096
- author
- Jirenhed, Dan-Anders LU and Hesslow, Germund LU
- organization
- publishing date
- 2016-08
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Purkinje cells . Classical conditioning . Cerebellum . Simple spikes . Timing
- in
- Cerebellum
- volume
- 15
- issue
- 4
- pages
- 526 - 534
- publisher
- Informa Healthcare
- external identifiers
-
- pmid:26400585
- scopus:84944699334
- pmid:26400585
- wos:000382928400014
- ISSN
- 1473-4230
- DOI
- 10.1007/s12311-015-0722-4
- project
- Thinking in Time: Cognition, Communication and Learning
- language
- English
- LU publication?
- yes
- id
- 7fb6d712-7934-46ca-abef-58774dca737a (old id 8035096)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26400585?dopt=Abstract
- date added to LUP
- 2016-04-04 08:54:29
- date last changed
- 2022-05-16 12:08:52
@article{7fb6d712-7934-46ca-abef-58774dca737a,
abstract = {{Several lines of evidence show that classical or Pavlovian conditioning of blink responses depends on the cerebellum. Recordings from cerebellar Purkinje cells that control the eyelid and the conditioned blink show that during training with a conditioning protocol, a Purkinje cell develops a pause response to the conditional stimulus. This conditioned cellular response has many of the properties that characterise the overt blink. The present paper argues that the learned Purkinje cell pause response is the memory trace and main driver of the overt conditioned blink and that it explains many well-known behavioural phenomena.}},
author = {{Jirenhed, Dan-Anders and Hesslow, Germund}},
issn = {{1473-4230}},
keywords = {{Purkinje cells . Classical conditioning . Cerebellum . Simple spikes . Timing}},
language = {{eng}},
number = {{4}},
pages = {{526--534}},
publisher = {{Informa Healthcare}},
series = {{Cerebellum}},
title = {{Are Purkinje Cell Pauses Drivers of Classically Conditioned Blink Responses?}},
url = {{http://dx.doi.org/10.1007/s12311-015-0722-4}},
doi = {{10.1007/s12311-015-0722-4}},
volume = {{15}},
year = {{2016}},
}