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Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.

Olsson, A; Hellgren, M; Berntorp, Erik LU and Baghaei, F (2015) In Haemophilia 21(6). p.742-746
Abstract
Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Haemophilia
volume
21
issue
6
pages
742 - 746
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • pmid:26346645
  • wos:000363508900148
  • scopus:84946495640
ISSN
1351-8216
DOI
10.1111/hae.12796
language
English
LU publication?
yes
id
eb0a4ec6-6576-4d6a-ae15-262b2eaf9e1a (old id 8042921)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26346645?dopt=Abstract
date added to LUP
2015-10-04 16:35:13
date last changed
2017-11-19 03:11:03
@article{eb0a4ec6-6576-4d6a-ae15-262b2eaf9e1a,
  abstract     = {Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).},
  author       = {Olsson, A and Hellgren, M and Berntorp, Erik and Baghaei, F},
  issn         = {1351-8216},
  language     = {eng},
  number       = {6},
  pages        = {742--746},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Haemophilia},
  title        = {Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.},
  url          = {http://dx.doi.org/10.1111/hae.12796},
  volume       = {21},
  year         = {2015},
}