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Distribution and risk of the second discordant primary cancers combined after a specific first primary cancer in German and Swedish cancer registries.

Chen, Tianhui; Fallah, Mahdi; Jansen, Lina; Castro, Felipe A; Krilavicuite, Agne; Katalinic, Alexander; Eisemann, Nora; Emrich, Katharina; Holleczek, Bernd and Geiss, Karla, et al. (2015) In Cancer Letters 369(1). p.152-166
Abstract
We aimed at investigating the distribution and risk of all second discordant primary cancers (SDPCs) after a specific first primary cancer in Germany and Sweden to provide etiological understanding of SDPCs and insight into their incidence rates and recording practices. Among 1,537,004 survivors of first primary cancers in Germany and 588,103 in Sweden, overall 80,162 and 32,544 SDPCs were recorded, respectively. Standardized incidence ratios (SIRs) of all SDPCs were elevated at levels between 1.1 and 2.1 after 23 (out of overall 29) cancers in Germany and at levels between 1.1 and 1.6 after 24 cancers in Sweden, and among them, elevated SIRs were found after 19 cancers in both populations. Decreased SIRs at levels ranging from 0.5 to 0.9... (More)
We aimed at investigating the distribution and risk of all second discordant primary cancers (SDPCs) after a specific first primary cancer in Germany and Sweden to provide etiological understanding of SDPCs and insight into their incidence rates and recording practices. Among 1,537,004 survivors of first primary cancers in Germany and 588,103 in Sweden, overall 80,162 and 32,544 SDPCs were recorded, respectively. Standardized incidence ratios (SIRs) of all SDPCs were elevated at levels between 1.1 and 2.1 after 23 (out of overall 29) cancers in Germany and at levels between 1.1 and 1.6 after 24 cancers in Sweden, and among them, elevated SIRs were found after 19 cancers in both populations. Decreased SIRs at levels ranging from 0.5 to 0.9 were found for some cancers with poor prognosis in Germany only. We found elevated risk after 19 out of 29 cancers in both countries, suggesting common etiology of SDPCs after most of first cancers and registration similarity. Decreased risks after some fatal cancers were found only in Germany, which may be attributed to reporting practices or missed death data in Germany. (Less)
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publication status
published
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Cancer Letters
volume
369
issue
1
pages
152 - 166
publisher
Elsevier
external identifiers
  • wos:000363819200018
  • pmid:26319898
  • scopus:84943449154
ISSN
1872-7980
DOI
10.1016/j.canlet.2015.08.014
language
English
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yes
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9f280bc4-52b8-4a59-a833-47e168b30170 (old id 8043726)
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http://www.ncbi.nlm.nih.gov/pubmed/26319898?dopt=Abstract
date added to LUP
2015-10-08 17:46:51
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2017-10-22 03:11:52
@article{9f280bc4-52b8-4a59-a833-47e168b30170,
  abstract     = {We aimed at investigating the distribution and risk of all second discordant primary cancers (SDPCs) after a specific first primary cancer in Germany and Sweden to provide etiological understanding of SDPCs and insight into their incidence rates and recording practices. Among 1,537,004 survivors of first primary cancers in Germany and 588,103 in Sweden, overall 80,162 and 32,544 SDPCs were recorded, respectively. Standardized incidence ratios (SIRs) of all SDPCs were elevated at levels between 1.1 and 2.1 after 23 (out of overall 29) cancers in Germany and at levels between 1.1 and 1.6 after 24 cancers in Sweden, and among them, elevated SIRs were found after 19 cancers in both populations. Decreased SIRs at levels ranging from 0.5 to 0.9 were found for some cancers with poor prognosis in Germany only. We found elevated risk after 19 out of 29 cancers in both countries, suggesting common etiology of SDPCs after most of first cancers and registration similarity. Decreased risks after some fatal cancers were found only in Germany, which may be attributed to reporting practices or missed death data in Germany.},
  author       = {Chen, Tianhui and Fallah, Mahdi and Jansen, Lina and Castro, Felipe A and Krilavicuite, Agne and Katalinic, Alexander and Eisemann, Nora and Emrich, Katharina and Holleczek, Bernd and Geiss, Karla and Eberle, Andrea and Sundquist, Jan and Brenner, Hermann and Hemminki, Kari},
  issn         = {1872-7980},
  language     = {eng},
  number       = {1},
  pages        = {152--166},
  publisher    = {Elsevier},
  series       = {Cancer Letters},
  title        = {Distribution and risk of the second discordant primary cancers combined after a specific first primary cancer in German and Swedish cancer registries.},
  url          = {http://dx.doi.org/10.1016/j.canlet.2015.08.014},
  volume       = {369},
  year         = {2015},
}