EpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseases
Lind, Lars ; Elmståhl, Sölve LU ; Bergman, Ebba ; Englund, Martin LU
; Lindberg, Eva
; Michaelsson, Karl
; Nilsson, Peter
LU
and Sundstrom, Johan
(2013)
In European Journal of Epidemiology
28(2).
p.189-197
- Abstract
- The most common diseases affecting middle-aged and elderly subjects in industrialized countries are multigenetic and lifestyle related. Several attempts have been made to study interactions between genes and lifestyle factors, but most such studies lack the power to examine interactions between several genes and several lifestyle components. The primary objective of the EpiHealth cohort study is to provide a resource to study interactions between several genotypes and lifestyle factors in a large cohort (the aim is 300,000 individuals) derived from the Swedish population in the age range of 45-75 years regarding development of common degenerative disorders, such as cardiovascular diseases, cancer, dementia, joint pain, obstructive lung... (More)
- The most common diseases affecting middle-aged and elderly subjects in industrialized countries are multigenetic and lifestyle related. Several attempts have been made to study interactions between genes and lifestyle factors, but most such studies lack the power to examine interactions between several genes and several lifestyle components. The primary objective of the EpiHealth cohort study is to provide a resource to study interactions between several genotypes and lifestyle factors in a large cohort (the aim is 300,000 individuals) derived from the Swedish population in the age range of 45-75 years regarding development of common degenerative disorders, such as cardiovascular diseases, cancer, dementia, joint pain, obstructive lung disease, depression, and osteoporotic fractures. The study consists of three parts. First, a collection of data on lifestyle factors by self-assessment using an internet-based questionnaire. Second, a visit to a test center where blood samples are collected and physiological parameters recorded. Third, the sample is followed for occurrence of outcomes using nationwide medical registers. This overview presents the study design and some baseline characteristics from the first year of data collection in the EpiHealth study. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3765217
- author
- Lind, Lars
; Elmståhl, Sölve
LU
; Bergman, Ebba
; Englund, Martin
LU
; Lindberg, Eva
; Michaelsson, Karl
; Nilsson, Peter
LU
and Sundstrom, Johan
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Epidemiology, Lifestyle, Gene, Prospective, Cohort study
- in
- European Journal of Epidemiology
- volume
- 28
- issue
- 2
- pages
- 189 - 197
- publisher
- Springer
- external identifiers
-
- wos:000316638900009
- scopus:84879502324
- ISSN
- 1573-7284
- DOI
- 10.1007/s10654-013-9787-x
- language
- English
- LU publication?
- yes
- id
- 810bd522-d278-4220-822b-bb5ccb0135e6 (old id 3765217)
- date added to LUP
- 2016-04-01 10:28:51
- date last changed
- 2022-04-27 22:36:12
@article{810bd522-d278-4220-822b-bb5ccb0135e6,
abstract = {{The most common diseases affecting middle-aged and elderly subjects in industrialized countries are multigenetic and lifestyle related. Several attempts have been made to study interactions between genes and lifestyle factors, but most such studies lack the power to examine interactions between several genes and several lifestyle components. The primary objective of the EpiHealth cohort study is to provide a resource to study interactions between several genotypes and lifestyle factors in a large cohort (the aim is 300,000 individuals) derived from the Swedish population in the age range of 45-75 years regarding development of common degenerative disorders, such as cardiovascular diseases, cancer, dementia, joint pain, obstructive lung disease, depression, and osteoporotic fractures. The study consists of three parts. First, a collection of data on lifestyle factors by self-assessment using an internet-based questionnaire. Second, a visit to a test center where blood samples are collected and physiological parameters recorded. Third, the sample is followed for occurrence of outcomes using nationwide medical registers. This overview presents the study design and some baseline characteristics from the first year of data collection in the EpiHealth study.}},
author = {{Lind, Lars and Elmståhl, Sölve and Bergman, Ebba and Englund, Martin and Lindberg, Eva and Michaelsson, Karl and Nilsson, Peter and Sundstrom, Johan}},
issn = {{1573-7284}},
keywords = {{Epidemiology; Lifestyle; Gene; Prospective; Cohort study}},
language = {{eng}},
number = {{2}},
pages = {{189--197}},
publisher = {{Springer}},
series = {{European Journal of Epidemiology}},
title = {{EpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseases}},
url = {{http://dx.doi.org/10.1007/s10654-013-9787-x}},
doi = {{10.1007/s10654-013-9787-x}},
volume = {{28}},
year = {{2013}},
}