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Quantification of normal cerebral oxygen extraction and oxygen metabolism by phase-based MRI susceptometry: evaluation of repeatability using two different imaging protocols.

Kämpe, Robin; Lind, Emelie LU ; Ståhlberg, Freddy LU ; van Westen, Danielle LU ; Knutsson, Linda LU and Wirestam, Ronnie LU (2017) In Clinical Physiology and Functional Imaging2002-01-01+01:00 37(2). p.220-2011
Abstract
Global oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2 ) were quantified in a test-retest study. Cerebral blood flow (CBF) data, required for CMRO2 estimation, were obtained using dynamic susceptibility contrast MRI (DSC-MRI). OEF and CMRO2 were quantified using two separate data sets, that is, conventional high-resolution (HR) gradient echo (GRE) phase maps as well as echo planar imaging (EPI) phase maps taken from the baseline (precontrast) part of the DSC-MRI time series. The EPI phase data were included to elucidate whether an extra HR-GRE scan is needed to obtain information about OEF and CMRO2 , or if this information can be extracted from the DSC-MRI experiment only.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Physiology and Functional Imaging2002-01-01+01:00
volume
37
issue
2
pages
220 - 2011
publisher
Wiley Online Library
external identifiers
  • pmid:26490359
  • scopus:84950139684
  • wos:000395108400017
ISSN
1475-0961
DOI
10.1111/cpf.12288
language
English
LU publication?
yes
id
0d92e17e-1bbf-4ca0-a7c1-73dc80687075 (old id 8148703)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26490359?dopt=Abstract
date added to LUP
2015-11-03 19:00:22
date last changed
2018-01-21 04:03:26
@article{0d92e17e-1bbf-4ca0-a7c1-73dc80687075,
  abstract     = {Global oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2 ) were quantified in a test-retest study. Cerebral blood flow (CBF) data, required for CMRO2 estimation, were obtained using dynamic susceptibility contrast MRI (DSC-MRI). OEF and CMRO2 were quantified using two separate data sets, that is, conventional high-resolution (HR) gradient echo (GRE) phase maps as well as echo planar imaging (EPI) phase maps taken from the baseline (precontrast) part of the DSC-MRI time series. The EPI phase data were included to elucidate whether an extra HR-GRE scan is needed to obtain information about OEF and CMRO2 , or if this information can be extracted from the DSC-MRI experiment only.},
  author       = {Kämpe, Robin and Lind, Emelie and Ståhlberg, Freddy and van Westen, Danielle and Knutsson, Linda and Wirestam, Ronnie},
  issn         = {1475-0961},
  language     = {eng},
  number       = {2},
  pages        = {220--2011},
  publisher    = {Wiley Online Library},
  series       = {Clinical Physiology and Functional Imaging2002-01-01+01:00},
  title        = {Quantification of normal cerebral oxygen extraction and oxygen metabolism by phase-based MRI susceptometry: evaluation of repeatability using two different imaging protocols.},
  url          = {http://dx.doi.org/10.1111/cpf.12288},
  volume       = {37},
  year         = {2017},
}