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Quantification of normal cerebral oxygen extraction and oxygen metabolism by phase-based MRI susceptometry: evaluation of repeatability using two different imaging protocols.

Kämpe, Robin ; Lind, Emelie LU ; Ståhlberg, Freddy LU ; van Westen, Danielle LU orcid ; Knutsson, Linda LU orcid and Wirestam, Ronnie LU orcid (2017) In Clinical Physiology and Functional Imaging 37(2). p.220-2011
Abstract
Global oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2 ) were quantified in a test-retest study. Cerebral blood flow (CBF) data, required for CMRO2 estimation, were obtained using dynamic susceptibility contrast MRI (DSC-MRI). OEF and CMRO2 were quantified using two separate data sets, that is, conventional high-resolution (HR) gradient echo (GRE) phase maps as well as echo planar imaging (EPI) phase maps taken from the baseline (precontrast) part of the DSC-MRI time series. The EPI phase data were included to elucidate whether an extra HR-GRE scan is needed to obtain information about OEF and CMRO2 , or if this information can be extracted from the DSC-MRI experiment only.
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Physiology and Functional Imaging
volume
37
issue
2
pages
220 - 2011
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:26490359
  • scopus:84950139684
  • pmid:26490359
  • wos:000395108400017
ISSN
1475-0961
DOI
10.1111/cpf.12288
language
English
LU publication?
yes
id
0d92e17e-1bbf-4ca0-a7c1-73dc80687075 (old id 8148703)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26490359?dopt=Abstract
date added to LUP
2016-04-04 08:55:24
date last changed
2022-04-23 18:26:02
@article{0d92e17e-1bbf-4ca0-a7c1-73dc80687075,
  abstract     = {{Global oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2 ) were quantified in a test-retest study. Cerebral blood flow (CBF) data, required for CMRO2 estimation, were obtained using dynamic susceptibility contrast MRI (DSC-MRI). OEF and CMRO2 were quantified using two separate data sets, that is, conventional high-resolution (HR) gradient echo (GRE) phase maps as well as echo planar imaging (EPI) phase maps taken from the baseline (precontrast) part of the DSC-MRI time series. The EPI phase data were included to elucidate whether an extra HR-GRE scan is needed to obtain information about OEF and CMRO2 , or if this information can be extracted from the DSC-MRI experiment only.}},
  author       = {{Kämpe, Robin and Lind, Emelie and Ståhlberg, Freddy and van Westen, Danielle and Knutsson, Linda and Wirestam, Ronnie}},
  issn         = {{1475-0961}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{220--2011}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Clinical Physiology and Functional Imaging}},
  title        = {{Quantification of normal cerebral oxygen extraction and oxygen metabolism by phase-based MRI susceptometry: evaluation of repeatability using two different imaging protocols.}},
  url          = {{https://lup.lub.lu.se/search/files/8474974/5210529_.pdf}},
  doi          = {{10.1111/cpf.12288}},
  volume       = {{37}},
  year         = {{2017}},
}