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Deletion of 14q in non‐Hodgkin's lymphoma

Kristoffersson, Ulf LU ; Heim, Sverre LU ; Johnsson, Anna ; Mandahl, Nils LU ; Olsson, Hakan LU orcid ; Åkerman, Måns LU and Mitelman, Felix LU orcid (1990) In European Journal of Haematology 44(4). p.261-264
Abstract

Abstract: 6 patients with non‐Hodgkin's lymphoma [3 with small cell lymphocytic lymphoma of B‐cell type (SL), and 1 each with follicular centroblastic/centrocytic, centroblastic, and immunoblastic lymphoma] and with the acquired cytogenetic abnormalities del(14) (q22) or del(14) (q24) are described. An evaluation of these 6 cases and 41 other lymphatic neoplasms with 14q deletion known from the literature revealed that 37 had a breakpoint in bands q22 to q24. The deletions occur significantly more often in lymphomas of SL morphology and in the leukemic counterpart, chronic lymphocytic leukemia, than in other types of lymphatic malignancies (p< 0.001).

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
keywords
B‐CLL, chromosome 14, chromosome deletion, non‐Hodgkin's lymphoma
in
European Journal of Haematology
volume
44
issue
4
pages
4 pages
publisher
Wiley-Blackwell
external identifiers
  • scopus:0025341668
  • pmid:2344888
ISSN
0902-4441
DOI
10.1111/j.1600-0609.1990.tb00390.x
language
English
LU publication?
yes
id
82ffa762-eb2b-4d89-a50e-cacf9b7b2b5a
date added to LUP
2018-12-19 13:35:15
date last changed
2024-01-15 10:23:02
@article{82ffa762-eb2b-4d89-a50e-cacf9b7b2b5a,
  abstract     = {{<p>Abstract:  6 patients with non‐Hodgkin's lymphoma [3 with small cell lymphocytic lymphoma of B‐cell type (SL), and 1 each with follicular centroblastic/centrocytic, centroblastic, and immunoblastic lymphoma] and with the acquired cytogenetic abnormalities del(14) (q22) or del(14) (q24) are described. An evaluation of these 6 cases and 41 other lymphatic neoplasms with 14q deletion known from the literature revealed that 37 had a breakpoint in bands q22 to q24. The deletions occur significantly more often in lymphomas of SL morphology and in the leukemic counterpart, chronic lymphocytic leukemia, than in other types of lymphatic malignancies (p&lt; 0.001).</p>}},
  author       = {{Kristoffersson, Ulf and Heim, Sverre and Johnsson, Anna and Mandahl, Nils and Olsson, Hakan and Åkerman, Måns and Mitelman, Felix}},
  issn         = {{0902-4441}},
  keywords     = {{B‐CLL; chromosome 14; chromosome deletion; non‐Hodgkin's lymphoma}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{4}},
  pages        = {{261--264}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{European Journal of Haematology}},
  title        = {{Deletion of 14q in non‐Hodgkin's lymphoma}},
  url          = {{http://dx.doi.org/10.1111/j.1600-0609.1990.tb00390.x}},
  doi          = {{10.1111/j.1600-0609.1990.tb00390.x}},
  volume       = {{44}},
  year         = {{1990}},
}