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Solute transfer in on-line analytical flow-through dialyzers

Bernhardsson, Bo LU orcid ; Johansson, Gillis LU and Martins, Eduardo (1985) In Analytica Chimica Acta 167. p.111-122
Abstract
Mass transfer in infinite parallel-plate dialyzers with co-flow between sample and detector streams is discussed for three different theoretical models. Analytical solutions with coupled diffusion and membrane transfer equations were obtained for plug flow in both channels. The finite-difference approximation method was used to obtain numerical solutions for a laminar-flow regime. Results obtained with a mixing-cup model under steady-state conditions were also included. With the dimensions typical for analytical dialyzers, there were only small differences between the laminar-flow and plug-flow models. The mixing-cup model predicted higher fluxes through the membrane than the other two models, particularly when the channel heights were... (More)
Mass transfer in infinite parallel-plate dialyzers with co-flow between sample and detector streams is discussed for three different theoretical models. Analytical solutions with coupled diffusion and membrane transfer equations were obtained for plug flow in both channels. The finite-difference approximation method was used to obtain numerical solutions for a laminar-flow regime. Results obtained with a mixing-cup model under steady-state conditions were also included. With the dimensions typical for analytical dialyzers, there were only small differences between the laminar-flow and plug-flow models. The mixing-cup model predicted higher fluxes through the membrane than the other two models, particularly when the channel heights were increased. The theoretical results were compared with experimental results for dialysis of zinc(II) ions and the flow dependence agreed reasonably well with theory provided that the hydrostatic pressures were equal on both sides, and that stresses which could result in membrane bulging were kept low.
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Analytica Chimica Acta
volume
167
pages
111 - 122
publisher
Elsevier
external identifiers
  • scopus:0039536754
ISSN
1873-4324
DOI
10.1016/S0003-2670(00)84414-1
language
English
LU publication?
yes
id
836cf2be-5615-4490-af74-92e7f824b115
date added to LUP
2017-08-02 13:07:27
date last changed
2021-01-03 03:18:35
@article{836cf2be-5615-4490-af74-92e7f824b115,
  abstract     = {{Mass transfer in infinite parallel-plate dialyzers with co-flow between sample and detector streams is discussed for three different theoretical models. Analytical solutions with coupled diffusion and membrane transfer equations were obtained for plug flow in both channels. The finite-difference approximation method was used to obtain numerical solutions for a laminar-flow regime. Results obtained with a mixing-cup model under steady-state conditions were also included. With the dimensions typical for analytical dialyzers, there were only small differences between the laminar-flow and plug-flow models. The mixing-cup model predicted higher fluxes through the membrane than the other two models, particularly when the channel heights were increased. The theoretical results were compared with experimental results for dialysis of zinc(II) ions and the flow dependence agreed reasonably well with theory provided that the hydrostatic pressures were equal on both sides, and that stresses which could result in membrane bulging were kept low.<br/>Download full text in PDF}},
  author       = {{Bernhardsson, Bo and Johansson, Gillis and Martins, Eduardo}},
  issn         = {{1873-4324}},
  language     = {{eng}},
  pages        = {{111--122}},
  publisher    = {{Elsevier}},
  series       = {{Analytica Chimica Acta}},
  title        = {{Solute transfer in on-line analytical flow-through dialyzers}},
  url          = {{https://lup.lub.lu.se/search/files/29062945/bernhar84.pdf}},
  doi          = {{10.1016/S0003-2670(00)84414-1}},
  volume       = {{167}},
  year         = {{1985}},
}