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From Data to Action: Neuroepidemiology Informs Implementation Research for Global Stroke Prevention and Treatment

Mensah, George A.; Sacco, Ralph L.; Vickrey, Barbara G.; Sampson, Uchechukwu K. A.; Waddy, Salina; Ovbiagele, Bruce; Pandian, Jeyaraj Durai; Norrving, Bo LU and Feigin, Valery L. (2015) In Neuroepidemiology 45(3). p.221-229
Abstract
As a scientific field of study, neuroepidemiology encompasses more than just the descriptive study of the frequency, distribution, determinants and outcomes of neurologic diseases in populations. It also includes experimental aspects that span the full spectrum of clinical and population science research. As such, neuroepidemiology has a strong potential to inform implementation research for global stroke prevention and treatment. This review begins with an overview of the progress that has been made in descriptive and experimental neuroepidemiology over the past quarter century with emphasis on standards for evidence generation, critical appraisal of that evidence and impact on clinical and public health practice at the national, regional... (More)
As a scientific field of study, neuroepidemiology encompasses more than just the descriptive study of the frequency, distribution, determinants and outcomes of neurologic diseases in populations. It also includes experimental aspects that span the full spectrum of clinical and population science research. As such, neuroepidemiology has a strong potential to inform implementation research for global stroke prevention and treatment. This review begins with an overview of the progress that has been made in descriptive and experimental neuroepidemiology over the past quarter century with emphasis on standards for evidence generation, critical appraisal of that evidence and impact on clinical and public health practice at the national, regional and global levels. Specific advances made in high-income countries as well as in low- and middle-income countries are presented. Gaps in implementation as well as evidence gaps in stroke research, stroke burden, clinical outcomes and disparities between developed and developing countries are then described. The continuing need for high quality neuroepidemiologic data in low- and middle-income countries is highlighted. Additionally, persisting disparities in stroke burden and care by sex, race, ethnicity, income and socioeconomic status are discussed. The crucial role that national stroke registries have played in neuroepidemiologic research is also addressed. Opportunities presented by new directions in comparative effectiveness and implementation research are discussed as avenues for turning neuroepidemiological insights into action to maximize health impact and to guide further biomedical research on neurological diseases. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Health policy development, Stroke epidemiology, Neuroepidemiology, Implementation research, Health inequities, country, Developing, Pragmatic trials, Comparative effectiveness research
in
Neuroepidemiology
volume
45
issue
3
pages
221 - 229
publisher
Karger
external identifiers
  • wos:000364221500009
  • scopus:84946100830
ISSN
1423-0208
DOI
10.1159/000441105
language
English
LU publication?
yes
id
b584b154-fcca-4e99-ae76-7c18c24b1536 (old id 8398150)
date added to LUP
2016-01-04 07:07:17
date last changed
2017-01-01 03:53:00
@article{b584b154-fcca-4e99-ae76-7c18c24b1536,
  abstract     = {As a scientific field of study, neuroepidemiology encompasses more than just the descriptive study of the frequency, distribution, determinants and outcomes of neurologic diseases in populations. It also includes experimental aspects that span the full spectrum of clinical and population science research. As such, neuroepidemiology has a strong potential to inform implementation research for global stroke prevention and treatment. This review begins with an overview of the progress that has been made in descriptive and experimental neuroepidemiology over the past quarter century with emphasis on standards for evidence generation, critical appraisal of that evidence and impact on clinical and public health practice at the national, regional and global levels. Specific advances made in high-income countries as well as in low- and middle-income countries are presented. Gaps in implementation as well as evidence gaps in stroke research, stroke burden, clinical outcomes and disparities between developed and developing countries are then described. The continuing need for high quality neuroepidemiologic data in low- and middle-income countries is highlighted. Additionally, persisting disparities in stroke burden and care by sex, race, ethnicity, income and socioeconomic status are discussed. The crucial role that national stroke registries have played in neuroepidemiologic research is also addressed. Opportunities presented by new directions in comparative effectiveness and implementation research are discussed as avenues for turning neuroepidemiological insights into action to maximize health impact and to guide further biomedical research on neurological diseases.},
  author       = {Mensah, George A. and Sacco, Ralph L. and Vickrey, Barbara G. and Sampson, Uchechukwu K. A. and Waddy, Salina and Ovbiagele, Bruce and Pandian, Jeyaraj Durai and Norrving, Bo and Feigin, Valery L.},
  issn         = {1423-0208},
  keyword      = {Health policy development,Stroke epidemiology,Neuroepidemiology,Implementation research,Health inequities,country,Developing,Pragmatic trials,Comparative effectiveness research},
  language     = {eng},
  number       = {3},
  pages        = {221--229},
  publisher    = {Karger},
  series       = {Neuroepidemiology},
  title        = {From Data to Action: Neuroepidemiology Informs Implementation Research for Global Stroke Prevention and Treatment},
  url          = {http://dx.doi.org/10.1159/000441105},
  volume       = {45},
  year         = {2015},
}