Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy
(2004) In Journal of Biomedical Optics 9(3). p.553-557- Abstract
- The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a period of 1 month. The calibration was robust when faced with adjustment of reference cell intensity and did not require a daily measured reference spectrum. The root-mean-square error of prediction of urea was 0.4 mM based on a two-factor partial least-squares regression model. (C) 2004 Society of Photo-Optical Instrumentation Engineers.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/279400
- author
- Jensen, PS ; Bak, J ; Ladefoged, S ; Andersson-Engels, Stefan LU and Friis-Hansen, L
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- online, dialysis, spectroscopy, dual-beam, near-infrared, urea
- in
- Journal of Biomedical Optics
- volume
- 9
- issue
- 3
- pages
- 553 - 557
- publisher
- SPIE
- external identifiers
-
- wos:000221304400016
- scopus:2942729885
- ISSN
- 1083-3668
- DOI
- 10.1117/1.1689337
- language
- English
- LU publication?
- yes
- id
- 851e092f-9713-4745-af3f-9f5cb3679110 (old id 279400)
- date added to LUP
- 2016-04-01 12:12:59
- date last changed
- 2022-01-27 00:33:00
@article{851e092f-9713-4745-af3f-9f5cb3679110, abstract = {{The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a period of 1 month. The calibration was robust when faced with adjustment of reference cell intensity and did not require a daily measured reference spectrum. The root-mean-square error of prediction of urea was 0.4 mM based on a two-factor partial least-squares regression model. (C) 2004 Society of Photo-Optical Instrumentation Engineers.}}, author = {{Jensen, PS and Bak, J and Ladefoged, S and Andersson-Engels, Stefan and Friis-Hansen, L}}, issn = {{1083-3668}}, keywords = {{online; dialysis; spectroscopy; dual-beam; near-infrared; urea}}, language = {{eng}}, number = {{3}}, pages = {{553--557}}, publisher = {{SPIE}}, series = {{Journal of Biomedical Optics}}, title = {{Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy}}, url = {{https://lup.lub.lu.se/search/files/2830778/2370288.pdf}}, doi = {{10.1117/1.1689337}}, volume = {{9}}, year = {{2004}}, }