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Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

Gillberg, Linn; Perfilyev, Alexander LU ; Brøns, Charlotte; Thomasen, Martin; Grunnet, Louise G; Volkov, Petr LU ; Rosqvist, Fredrik; Iggman, David; Dahlman, Ingrid and Risérus, Ulf, et al. (2016) In Diabetologia 59(4). p.799-812
Abstract
Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.
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type
Contribution to journal
publication status
published
subject
in
Diabetologia
volume
59
issue
4
pages
799 - 812
publisher
Springer Verlag
external identifiers
  • pmid:26750116
  • scopus:84959547501
  • wos:000371802700018
ISSN
1432-0428
DOI
10.1007/s00125-015-3852-9
language
English
LU publication?
yes
id
68fb1fba-7708-460e-b2b5-6b601fedf1c3 (old id 8592468)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26750116?dopt=Abstract
date added to LUP
2016-02-02 21:22:44
date last changed
2017-10-22 04:53:11
@article{68fb1fba-7708-460e-b2b5-6b601fedf1c3,
  abstract     = {Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.},
  author       = {Gillberg, Linn and Perfilyev, Alexander and Brøns, Charlotte and Thomasen, Martin and Grunnet, Louise G and Volkov, Petr and Rosqvist, Fredrik and Iggman, David and Dahlman, Ingrid and Risérus, Ulf and Rönn, Tina and Nilsson, Emma A and Vaag, Allan and Ling, Charlotte},
  issn         = {1432-0428},
  language     = {eng},
  month        = {01},
  number       = {4},
  pages        = {799--812},
  publisher    = {Springer Verlag},
  series       = {Diabetologia},
  title        = {Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.},
  url          = {http://dx.doi.org/10.1007/s00125-015-3852-9},
  volume       = {59},
  year         = {2016},
}