A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. : A consecutive series of 55 cases.
(2019) In Journal of Bone and Joint Infection 4(6). p.285-291- Abstract
- AIM Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities. METHODS We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records. RESULTS Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was... (More)
- AIM Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities. METHODS We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records. RESULTS Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was given to 43 (78%) cases. Debridement with retention of the implant and antibiotics (DAIR) was the most common surgical treatment strategy (71%), with a cure-rate of 72%. Overall cure-rate was 67%, and in cases where cure was intended, this was achieved in 80%. CONCLUSIONS When cure is aimed for, the prognosis for enterococcal PJI is not so poor, and DAIR treatment can provide adequate results in many cases. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/861cecbe-edd2-4e0e-82bd-9193cf9bb6a0
- author
- Thompson, Olof LU ; Rasmussen, Magnus LU ; Stefansdottir, Anna LU ; Christensson, Bertil LU and Åkesson, Per LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Enterococcus faecalis; Enterococcus faecium; debridement; outcome; prosthetic joint infection; treatment
- in
- Journal of Bone and Joint Infection
- volume
- 4
- issue
- 6
- pages
- 7 pages
- publisher
- Copernicus GmbH
- external identifiers
-
- scopus:85089258008
- ISSN
- 2206-3552
- DOI
- 10.7150/jbji.35683
- language
- English
- LU publication?
- yes
- id
- 861cecbe-edd2-4e0e-82bd-9193cf9bb6a0
- date added to LUP
- 2021-01-27 08:36:51
- date last changed
- 2022-09-10 01:39:32
@article{861cecbe-edd2-4e0e-82bd-9193cf9bb6a0, abstract = {{AIM Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities. METHODS We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records. RESULTS Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was given to 43 (78%) cases. Debridement with retention of the implant and antibiotics (DAIR) was the most common surgical treatment strategy (71%), with a cure-rate of 72%. Overall cure-rate was 67%, and in cases where cure was intended, this was achieved in 80%. CONCLUSIONS When cure is aimed for, the prognosis for enterococcal PJI is not so poor, and DAIR treatment can provide adequate results in many cases.}}, author = {{Thompson, Olof and Rasmussen, Magnus and Stefansdottir, Anna and Christensson, Bertil and Åkesson, Per}}, issn = {{2206-3552}}, keywords = {{Enterococcus faecalis; Enterococcus faecium; debridement; outcome; prosthetic joint infection; treatment}}, language = {{eng}}, number = {{6}}, pages = {{285--291}}, publisher = {{Copernicus GmbH}}, series = {{Journal of Bone and Joint Infection}}, title = {{A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. : A consecutive series of 55 cases.}}, url = {{http://dx.doi.org/10.7150/jbji.35683}}, doi = {{10.7150/jbji.35683}}, volume = {{4}}, year = {{2019}}, }