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A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. : A consecutive series of 55 cases.

Thompson, Olof LU ; Rasmussen, Magnus LU ; Stefansdottir, Anna LU ; Christensson, Bertil LU and Åkesson, Per LU (2019) In Journal of Bone and Joint Infection 4(6). p.285-291
Abstract
AIM Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities. METHODS We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records. RESULTS Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was... (More)
AIM Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities. METHODS We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records. RESULTS Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was given to 43 (78%) cases. Debridement with retention of the implant and antibiotics (DAIR) was the most common surgical treatment strategy (71%), with a cure-rate of 72%. Overall cure-rate was 67%, and in cases where cure was intended, this was achieved in 80%. CONCLUSIONS When cure is aimed for, the prognosis for enterococcal PJI is not so poor, and DAIR treatment can provide adequate results in many cases. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Enterococcus faecalis; Enterococcus faecium; debridement; outcome; prosthetic joint infection; treatment
in
Journal of Bone and Joint Infection
volume
4
issue
6
pages
7 pages
publisher
Copernicus GmbH
external identifiers
  • scopus:85089258008
ISSN
2206-3552
DOI
10.7150/jbji.35683
language
English
LU publication?
yes
id
861cecbe-edd2-4e0e-82bd-9193cf9bb6a0
date added to LUP
2021-01-27 08:36:51
date last changed
2022-09-10 01:39:32
@article{861cecbe-edd2-4e0e-82bd-9193cf9bb6a0,
  abstract     = {{AIM Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities. METHODS We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records. RESULTS Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was given to 43 (78%) cases. Debridement with retention of the implant and antibiotics (DAIR) was the most common surgical treatment strategy (71%), with a cure-rate of 72%. Overall cure-rate was 67%, and in cases where cure was intended, this was achieved in 80%. CONCLUSIONS When cure is aimed for, the prognosis for enterococcal PJI is not so poor, and DAIR treatment can provide adequate results in many cases.}},
  author       = {{Thompson, Olof and Rasmussen, Magnus and Stefansdottir, Anna and Christensson, Bertil and Åkesson, Per}},
  issn         = {{2206-3552}},
  keywords     = {{Enterococcus faecalis; Enterococcus faecium; debridement; outcome; prosthetic joint infection; treatment}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{285--291}},
  publisher    = {{Copernicus GmbH}},
  series       = {{Journal of Bone and Joint Infection}},
  title        = {{A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. : A consecutive series of 55 cases.}},
  url          = {{http://dx.doi.org/10.7150/jbji.35683}},
  doi          = {{10.7150/jbji.35683}},
  volume       = {{4}},
  year         = {{2019}},
}