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The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.

Podmore, Clara; Meidtner, Karina; Schulze, Matthias B; Scott, Robert A; Ramond, Anna; Butterworth, Adam S; Di Angelantonio, Emanuele; Danesh, John; Arriola, Larraitz and Barricarte, Aurelio, et al. (2016) In Diabetes Care 39(4). p.572-581
Abstract
Observational studies show an association between ferritin and type 2 diabetes (T2D), suggesting a role of high iron stores in T2D development. However, ferritin is influenced by factors other than iron stores, which is less the case for other biomarkers of iron metabolism. We investigate associations of ferritin, transferrin saturation (TSAT), serum iron, and transferrin with T2D incidence to clarify the role of iron in the pathogenesis of T2D.
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organization
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type
Contribution to journal
publication status
published
subject
in
Diabetes Care
volume
39
issue
4
pages
9 pages
publisher
American Diabetes Association
external identifiers
  • pmid:26861925
  • scopus:84962074006
  • wos:000376240400019
ISSN
1935-5548
DOI
10.2337/dc15-0257
language
English
LU publication?
yes
id
17898c1c-60ea-4ea0-9805-002e5edc85bc (old id 8825922)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26861925?dopt=Abstract
date added to LUP
2016-03-03 16:41:44
date last changed
2017-07-09 04:38:46
@article{17898c1c-60ea-4ea0-9805-002e5edc85bc,
  abstract     = {Observational studies show an association between ferritin and type 2 diabetes (T2D), suggesting a role of high iron stores in T2D development. However, ferritin is influenced by factors other than iron stores, which is less the case for other biomarkers of iron metabolism. We investigate associations of ferritin, transferrin saturation (TSAT), serum iron, and transferrin with T2D incidence to clarify the role of iron in the pathogenesis of T2D.},
  author       = {Podmore, Clara and Meidtner, Karina and Schulze, Matthias B and Scott, Robert A and Ramond, Anna and Butterworth, Adam S and Di Angelantonio, Emanuele and Danesh, John and Arriola, Larraitz and Barricarte, Aurelio and Boeing, Heiner and Clavel-Chapelon, Françoise and Cross, Amanda J and Dahm, Christina C and Fagherazzi, Guy and Franks, Paul and Gavrila, Diana and Grioni, Sara and Gunter, Marc J and Gusto, Gaelle and Jakszyn, Paula and Katzke, Verena and Key, Timothy J and Kühn, Tilman and Mattiello, Amalia and Nilsson, Peter and Olsen, Anja and Overvad, Kim and Palli, Domenico and Quirós, J Ramón and Rolandsson, Olov and Sacerdote, Carlotta and Sánchez-Cantalejo, Emilio and Slimani, Nadia and Sluijs, Ivonne and Spijkerman, Annemieke M W and Tjonneland, Anne and Tumino, Rosario and van der A, Daphne L and van der Schouw, Yvonne T and Feskens, Edith J M and Forouhi, Nita G and Sharp, Stephen J and Riboli, Elio and Langenberg, Claudia and Wareham, Nicholas J},
  issn         = {1935-5548},
  language     = {eng},
  number       = {4},
  pages        = {572--581},
  publisher    = {American Diabetes Association},
  series       = {Diabetes Care},
  title        = {The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.},
  url          = {http://dx.doi.org/10.2337/dc15-0257},
  volume       = {39},
  year         = {2016},
}