Protein Z and protein Z-dependent protease inhibitor - Determinants of levels and risk of venous thrombosis
(2005) In Thrombosis and Haemostasis 93(3). p.411-413- Abstract
- To assess the potential roles of protein Z (PZ) and protein Z-dependent protease inhibitor (ZPI) in venous thrombosis, their plasma levels were measured in 426 individuals with venous thrombosis and 471 control individuals participating in the Leiden Thrombophilia Study. A relationship between the level of PZ or ZPI and venous thrombosis was not detected in the overall case-control study. PZ and ZPI circulate as a complex and their plasma levels are interdependent. Both PZ and ZPI are increased with oral contraceptive use and reduced with oral anticoagulant therapy.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/896984
- author
- Al-Shanqeeti, A ; Vlieg, AV ; Berntorp, Erik LU ; Rosendaal, FR and Broze, GJ
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- thrombophilia, coagulation inhibitors, clinical/epidemiological studies
- in
- Thrombosis and Haemostasis
- volume
- 93
- issue
- 3
- pages
- 411 - 413
- publisher
- Schattauer GmbH
- external identifiers
-
- wos:000227808200004
- scopus:15344345528
- ISSN
- 0340-6245
- DOI
- 10.1160/TH04-11-0715
- language
- English
- LU publication?
- yes
- id
- 19642b49-799a-4b7d-839f-a9e8fca6aeab (old id 896984)
- alternative location
- https://www.openaccess.leidenuniv.nl/dspace/bitstream/1887/5054/1/2_303_440.pdf
- date added to LUP
- 2016-04-01 17:11:55
- date last changed
- 2022-04-23 03:25:34
@article{19642b49-799a-4b7d-839f-a9e8fca6aeab, abstract = {{To assess the potential roles of protein Z (PZ) and protein Z-dependent protease inhibitor (ZPI) in venous thrombosis, their plasma levels were measured in 426 individuals with venous thrombosis and 471 control individuals participating in the Leiden Thrombophilia Study. A relationship between the level of PZ or ZPI and venous thrombosis was not detected in the overall case-control study. PZ and ZPI circulate as a complex and their plasma levels are interdependent. Both PZ and ZPI are increased with oral contraceptive use and reduced with oral anticoagulant therapy.}}, author = {{Al-Shanqeeti, A and Vlieg, AV and Berntorp, Erik and Rosendaal, FR and Broze, GJ}}, issn = {{0340-6245}}, keywords = {{thrombophilia; coagulation inhibitors; clinical/epidemiological studies}}, language = {{eng}}, number = {{3}}, pages = {{411--413}}, publisher = {{Schattauer GmbH}}, series = {{Thrombosis and Haemostasis}}, title = {{Protein Z and protein Z-dependent protease inhibitor - Determinants of levels and risk of venous thrombosis}}, url = {{http://dx.doi.org/10.1160/TH04-11-0715}}, doi = {{10.1160/TH04-11-0715}}, volume = {{93}}, year = {{2005}}, }