Predictors and moderators of treatment outcome for single incident pediatric PTSD: A multi-center randomized clinical trial
de Roos, Carlijn ; Zijlstra, Bonne ; Perrin, Sean LU
; van der Oord, Saskia
; Lucassen, Sacha
; Emmelkamp, Paul
and de Jongh, Ad
(2021)
In European Journal of Psychotraumatology
12(1).
- Abstract
- BACKGROUND: The current study explores predictors and moderators of pediatric PTSD outcomes for Eye Movement Desensitization and Reprocessing Therapy (EMDR) and Cognitive Behavioral Writing Therapy (CBWT). METHODS: Data were obtained as part of a multi-center randomized controlled trial of up to six sessions (up to 45 minutes each) of either EMDR therapy, CBWT, or wait-list, involving 101 youth (aged 8-18 years) with a PTSD diagnosis (full/subthreshold) tied to a single event. The predictive and moderating effects of the child’s baseline sociodemographic and clinical characteristics, and parent’s psychopathology were evaluated using linear mixed models (LMM) from pre- to post-treatment and from pre- to 3- and 12-month follow-ups. RESULTS:... (More)
- BACKGROUND: The current study explores predictors and moderators of pediatric PTSD outcomes for Eye Movement Desensitization and Reprocessing Therapy (EMDR) and Cognitive Behavioral Writing Therapy (CBWT). METHODS: Data were obtained as part of a multi-center randomized controlled trial of up to six sessions (up to 45 minutes each) of either EMDR therapy, CBWT, or wait-list, involving 101 youth (aged 8-18 years) with a PTSD diagnosis (full/subthreshold) tied to a single event. The predictive and moderating effects of the child’s baseline sociodemographic and clinical characteristics, and parent’s psychopathology were evaluated using linear mixed models (LMM) from pre- to post-treatment and from pre- to 3- and 12-month follow-ups. RESULTS: At post-treatment and 3-month follow-up, youth with an index trauma of sexual abuse, severe symptoms of PTSD, anxiety, depression, more comorbid disorders, negative posttraumatic beliefs, and with a parent with more severe psychopathology fared worse in both treatments. For children with more severe self-reported PTSD symptoms at baseline, the (exploratory) moderator analysis showed that the EMDR group improved more than the CBWT group, with the opposite being true for children and parents with a less severe clinical profile. CONCLUSIONS: The most consistent finding from the predictor analyses was that parental symptomatology predicted poorer outcomes, suggesting that parents should be assessed, supported and referred for their own treatment where indicated. The effect of the significant moderator variables was time-limited, and given the large response rate (>90%) and brevity (< 4 hours) of both treatments, the present findings suggest a focus on implementation and dissemination, rather than tailoring, of evidence-based trauma-focused treatments for pediatric PTSD tied to a single event. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/89de4ced-9826-466b-b01b-6a25506219a8
- author
- de Roos, Carlijn
; Zijlstra, Bonne
; Perrin, Sean
LU
; van der Oord, Saskia
; Lucassen, Sacha
; Emmelkamp, Paul
and de Jongh, Ad
- organization
- publishing date
- 2021-07-27
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- EMDR, Trauma focused CBT, randomized controlled trial, outcome predictors, outcome moderators, PTSD, children and adolescents
- in
- European Journal of Psychotraumatology
- volume
- 12
- issue
- 1
- article number
- 1968138
- publisher
- Taylor & Francis
- external identifiers
-
- scopus:85116203131
- pmid:34621497
- ISSN
- 2000-8066
- DOI
- 10.1080/20008198.2021.1968138
- language
- English
- LU publication?
- yes
- id
- 89de4ced-9826-466b-b01b-6a25506219a8
- date added to LUP
- 2021-07-30 08:59:01
- date last changed
- 2022-04-27 02:53:04
@article{89de4ced-9826-466b-b01b-6a25506219a8,
abstract = {{BACKGROUND: The current study explores predictors and moderators of pediatric PTSD outcomes for Eye Movement Desensitization and Reprocessing Therapy (EMDR) and Cognitive Behavioral Writing Therapy (CBWT). METHODS: Data were obtained as part of a multi-center randomized controlled trial of up to six sessions (up to 45 minutes each) of either EMDR therapy, CBWT, or wait-list, involving 101 youth (aged 8-18 years) with a PTSD diagnosis (full/subthreshold) tied to a single event. The predictive and moderating effects of the child’s baseline sociodemographic and clinical characteristics, and parent’s psychopathology were evaluated using linear mixed models (LMM) from pre- to post-treatment and from pre- to 3- and 12-month follow-ups. RESULTS: At post-treatment and 3-month follow-up, youth with an index trauma of sexual abuse, severe symptoms of PTSD, anxiety, depression, more comorbid disorders, negative posttraumatic beliefs, and with a parent with more severe psychopathology fared worse in both treatments. For children with more severe self-reported PTSD symptoms at baseline, the (exploratory) moderator analysis showed that the EMDR group improved more than the CBWT group, with the opposite being true for children and parents with a less severe clinical profile. CONCLUSIONS: The most consistent finding from the predictor analyses was that parental symptomatology predicted poorer outcomes, suggesting that parents should be assessed, supported and referred for their own treatment where indicated. The effect of the significant moderator variables was time-limited, and given the large response rate (>90%) and brevity (< 4 hours) of both treatments, the present findings suggest a focus on implementation and dissemination, rather than tailoring, of evidence-based trauma-focused treatments for pediatric PTSD tied to a single event.}},
author = {{de Roos, Carlijn and Zijlstra, Bonne and Perrin, Sean and van der Oord, Saskia and Lucassen, Sacha and Emmelkamp, Paul and de Jongh, Ad}},
issn = {{2000-8066}},
keywords = {{EMDR; Trauma focused CBT; randomized controlled trial; outcome predictors; outcome moderators; PTSD; children and adolescents}},
language = {{eng}},
month = {{07}},
number = {{1}},
publisher = {{Taylor & Francis}},
series = {{European Journal of Psychotraumatology}},
title = {{Predictors and moderators of treatment outcome for single incident pediatric PTSD: A multi-center randomized clinical trial}},
url = {{http://dx.doi.org/10.1080/20008198.2021.1968138}},
doi = {{10.1080/20008198.2021.1968138}},
volume = {{12}},
year = {{2021}},
}