Advanced

Clinical use and limitations of non-invasive electrophysiological tests in patients with atrial fibrillation

Corino, Valentina D.A.; Sandberg, Frida LU ; Mainardi, Luca T.; Sörnmo, Leif LU and Platonov, Pyotr LU (2016) In JAFIB: Journal of Atrial Fibrillation 9(1).
Abstract
Atrial fibrillation (AF) is a complex arrhythmia, that has been studied non-invasively assessing atrial refractory period, atrioventricular node (AV) node refractory period, and ventricular response. The AV node plays a fundamental role as it filters many of the numerous irregular atrial impulses bombarding the node. Despite its importance, the electrophysiological (EP) characteristics of the AV node are not routinely evaluated since conventional EP techniques for assessment of refractory period or conduction velocity of the AV node are not applicable in AF. Since rate-control drugs control ventricular response through their effect on the AV node, noninvasive assessment of AV node electrophysiology may be useful. The RR series, though... (More)
Atrial fibrillation (AF) is a complex arrhythmia, that has been studied non-invasively assessing atrial refractory period, atrioventricular node (AV) node refractory period, and ventricular response. The AV node plays a fundamental role as it filters many of the numerous irregular atrial impulses bombarding the node. Despite its importance, the electrophysiological (EP) characteristics of the AV node are not routinely evaluated since conventional EP techniques for assessment of refractory period or conduction velocity of the AV node are not applicable in AF. Since rate-control drugs control ventricular response through their effect on the AV node, noninvasive assessment of AV node electrophysiology may be useful. The RR series, though being highly irregular, contains information that can be used for risk stratification and prediction of outcome. In particular, RR irregularity measures during AF have been shown to be related to clinical outcome. This paper reviews the attempts done to noninvasively characterize the AV node and the ventricular response, highlighting clinical applications and limitations of the noninvasive techniques. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
JAFIB: Journal of Atrial Fibrillation
volume
9
issue
1
publisher
Cardiofront, Inc.
ISSN
1941-6911
language
English
LU publication?
yes
id
8f44a1ba-de3a-4d5c-949e-977cd51efc51
alternative location
http://www.jafib.com/PMC/XML/Inprogress/1424/1424pdf_valentina_corino.pdf
date added to LUP
2017-08-09 14:48:24
date last changed
2017-09-19 16:38:53
@article{8f44a1ba-de3a-4d5c-949e-977cd51efc51,
  abstract     = {Atrial fibrillation (AF) is a complex arrhythmia, that has been studied non-invasively assessing atrial refractory period, atrioventricular node (AV) node refractory period, and ventricular response. The AV node plays a fundamental role as it filters many of the numerous irregular atrial impulses bombarding the node. Despite its importance, the electrophysiological (EP) characteristics of the AV node are not routinely evaluated since conventional EP techniques for assessment of refractory period or conduction velocity of the AV node are not applicable in AF. Since rate-control drugs control ventricular response through their effect on the AV node, noninvasive assessment of AV node electrophysiology may be useful. The RR series, though being highly irregular, contains information that can be used for risk stratification and prediction of outcome. In particular, RR irregularity measures during AF have been shown to be related to clinical outcome. This paper reviews the attempts done to noninvasively characterize the AV node and the ventricular response, highlighting clinical applications and limitations of the noninvasive techniques. },
  author       = {Corino, Valentina D.A. and Sandberg, Frida and Mainardi, Luca T. and Sörnmo, Leif and Platonov, Pyotr},
  issn         = {1941-6911},
  language     = {eng},
  number       = {1},
  publisher    = {Cardiofront, Inc.},
  series       = {JAFIB: Journal of Atrial Fibrillation},
  title        = {Clinical use and limitations of non-invasive electrophysiological tests in patients with atrial fibrillation},
  volume       = {9},
  year         = {2016},
}