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Prolonged opioid use after distal radius fracture

Larrosa Pardo, Fabian LU ; Bondesson, Elisabeth LU orcid ; Petersson, Ingemar F LU ; Schelin, Maria E C LU and Jöud, A LU orcid (2023) In European Journal of Pain 27(7). p.848-859
Abstract

BACKGROUND: Prolonged opioid use (more than 90 days) after injury puts the patient at risk for adverse effects. We investigated the patterns of opioid prescription after distal radius fracture and the effect of pre- and post-fracture factors on the risk for prolonged use.

METHODS: This register-based cohort study uses routinely collected health care data, including purchases of prescription opioids, in the county of Skåne, Sweden. 9369 adult patients with a radius fracture diagnosed 2015-2018 were followed for one year after fracture. We calculated proportions of patients with prolonged opioid use, both in total and according to different exposures. Using modified Poisson regression, we calculated adjusted risk ratios for the... (More)

BACKGROUND: Prolonged opioid use (more than 90 days) after injury puts the patient at risk for adverse effects. We investigated the patterns of opioid prescription after distal radius fracture and the effect of pre- and post-fracture factors on the risk for prolonged use.

METHODS: This register-based cohort study uses routinely collected health care data, including purchases of prescription opioids, in the county of Skåne, Sweden. 9369 adult patients with a radius fracture diagnosed 2015-2018 were followed for one year after fracture. We calculated proportions of patients with prolonged opioid use, both in total and according to different exposures. Using modified Poisson regression, we calculated adjusted risk ratios for the following exposures: previous opioid use, mental illness, consultation for pain, surgery for distal radius fracture and occupational/ physical therapy after fracture.

RESULTS: Prolonged opioid use (4-6 months after fracture) was found in 664 (7.1%) of the patients. A previous, but discontinued, regular use of opioids up to five years before fracture increased the risk compared to opioid naïve patients. Both regular and non-regular opioid use the year before fracture increased the risk. The risk was also higher for patients with mental illness, and those who were treated with surgery, we found no significant effect of pain consultation in previous year. Occupational/physical therapy lowered the risk for prolonged use.

CONCLUSION: Considering history of mental illness and previous opioid use while promoting rehabilitation can be important to prevent prolonged opioid use after distal radius fracture.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Pain
volume
27
issue
7
pages
848 - 859
publisher
Elsevier
external identifiers
  • scopus:85152001050
  • pmid:36970930
ISSN
1090-3801
DOI
10.1002/ejp.2114
language
English
LU publication?
yes
additional info
This article is protected by copyright. All rights reserved.
id
940ea6a4-99b9-48b5-830e-28a6a4dd0249
date added to LUP
2023-04-03 09:01:03
date last changed
2024-06-15 01:45:49
@article{940ea6a4-99b9-48b5-830e-28a6a4dd0249,
  abstract     = {{<p>BACKGROUND: Prolonged opioid use (more than 90 days) after injury puts the patient at risk for adverse effects. We investigated the patterns of opioid prescription after distal radius fracture and the effect of pre- and post-fracture factors on the risk for prolonged use.</p><p>METHODS: This register-based cohort study uses routinely collected health care data, including purchases of prescription opioids, in the county of Skåne, Sweden. 9369 adult patients with a radius fracture diagnosed 2015-2018 were followed for one year after fracture. We calculated proportions of patients with prolonged opioid use, both in total and according to different exposures. Using modified Poisson regression, we calculated adjusted risk ratios for the following exposures: previous opioid use, mental illness, consultation for pain, surgery for distal radius fracture and occupational/ physical therapy after fracture.</p><p>RESULTS: Prolonged opioid use (4-6 months after fracture) was found in 664 (7.1%) of the patients. A previous, but discontinued, regular use of opioids up to five years before fracture increased the risk compared to opioid naïve patients. Both regular and non-regular opioid use the year before fracture increased the risk. The risk was also higher for patients with mental illness, and those who were treated with surgery, we found no significant effect of pain consultation in previous year. Occupational/physical therapy lowered the risk for prolonged use.</p><p>CONCLUSION: Considering history of mental illness and previous opioid use while promoting rehabilitation can be important to prevent prolonged opioid use after distal radius fracture.</p>}},
  author       = {{Larrosa Pardo, Fabian and Bondesson, Elisabeth and Petersson, Ingemar F and Schelin, Maria E C and Jöud, A}},
  issn         = {{1090-3801}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{7}},
  pages        = {{848--859}},
  publisher    = {{Elsevier}},
  series       = {{European Journal of Pain}},
  title        = {{Prolonged opioid use after distal radius fracture}},
  url          = {{http://dx.doi.org/10.1002/ejp.2114}},
  doi          = {{10.1002/ejp.2114}},
  volume       = {{27}},
  year         = {{2023}},
}