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Ny in vitro-analys prövad: Blödningstid fortfarande bästa metod för test av den primära hemostasen

Ridefelt, P ; Egberg, N ; Hillarp, A LU ; Lethagen, S LU and Tengborn, L LU (2001) In Lakartidningen 98(37). p.4-3922
Abstract

The need is great for a simple, cheap and readily accessible method for the evaluation of primary hemostasis in work-ups at both out-patient clinics and units caring for surgical or intensive care patients. PFA-100 is a recently introduced instrument for in vitro testing of platelet function. We report experiences from Stockholm, Gothenburg and Malmo of PFA-100 measurements performed on samples from healthy controls and from patients with von Willebrand disease or platelet disorders. It is shown that the PFA-100 system has a high sensitivity for von Willebrands disease, while the sensitivity for hereditary platelet dysfunction is low. In its present design this new device could not replace the template bleeding time as a screening test... (More)

The need is great for a simple, cheap and readily accessible method for the evaluation of primary hemostasis in work-ups at both out-patient clinics and units caring for surgical or intensive care patients. PFA-100 is a recently introduced instrument for in vitro testing of platelet function. We report experiences from Stockholm, Gothenburg and Malmo of PFA-100 measurements performed on samples from healthy controls and from patients with von Willebrand disease or platelet disorders. It is shown that the PFA-100 system has a high sensitivity for von Willebrands disease, while the sensitivity for hereditary platelet dysfunction is low. In its present design this new device could not replace the template bleeding time as a screening test for primary hemostasis.

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Please use this url to cite or link to this publication:
author
; ; ; and
organization
alternative title
New in vitro analysis tested : bleeding time is still the best method for evaluation of primary hemostasis
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bleeding Time/methods, Blood Platelet Disorders/blood, Hemostasis, Humans, Platelet Function Tests/instrumentation, Sensitivity and Specificity
in
Lakartidningen
volume
98
issue
37
pages
4 - 3922
publisher
Swedish Medical Association
external identifiers
  • pmid:11586831
  • scopus:0035850657
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
9492f2ed-cbf8-4f1f-a5da-40a6e9d09f52
alternative location
https://lakartidningen.se/wp-content/uploads/OldPdfFiles/2001/23402.pdf
date added to LUP
2022-08-29 10:22:41
date last changed
2024-05-02 14:27:45
@article{9492f2ed-cbf8-4f1f-a5da-40a6e9d09f52,
  abstract     = {{<p>The need is great for a simple, cheap and readily accessible method for the evaluation of primary hemostasis in work-ups at both out-patient clinics and units caring for surgical or intensive care patients. PFA-100 is a recently introduced instrument for in vitro testing of platelet function. We report experiences from Stockholm, Gothenburg and Malmo of PFA-100 measurements performed on samples from healthy controls and from patients with von Willebrand disease or platelet disorders. It is shown that the PFA-100 system has a high sensitivity for von Willebrands disease, while the sensitivity for hereditary platelet dysfunction is low. In its present design this new device could not replace the template bleeding time as a screening test for primary hemostasis.</p>}},
  author       = {{Ridefelt, P and Egberg, N and Hillarp, A and Lethagen, S and Tengborn, L}},
  issn         = {{0023-7205}},
  keywords     = {{Bleeding Time/methods; Blood Platelet Disorders/blood; Hemostasis; Humans; Platelet Function Tests/instrumentation; Sensitivity and Specificity}},
  language     = {{swe}},
  month        = {{09}},
  number       = {{37}},
  pages        = {{4--3922}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Lakartidningen}},
  title        = {{Ny in vitro-analys prövad: Blödningstid fortfarande bästa metod för test av den primära hemostasen}},
  url          = {{https://lakartidningen.se/wp-content/uploads/OldPdfFiles/2001/23402.pdf}},
  volume       = {{98}},
  year         = {{2001}},
}