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Malmö POTS symptom score : Assessing symptom burden in postural orthostatic tachycardia syndrome

Medic Spahic, Jasmina LU ; Hamrefors, Viktor LU orcid ; Johansson, Madeleine LU orcid ; Ricci, Fabrizio LU ; Melander, Olle LU orcid ; Sutton, Richard and Fedorowski, Artur LU orcid (2022) Annual Congress of Italian Society of Cardiology In European Heart Journal, Supplement 24(Supplement K).
Abstract
Background
Postural orthostatic tachycardia syndrome (POTS) is a common cardiovascular autonomic disorder characterized by excessive heart rate increase on standing and symptoms of orthostatic intolerance, posing significant limitations on functional capacity. No objective tool exists to classify symptom burden in POTS.

Methods
We conducted a case-control study in 62 POTS patients and 50 healthy controls to compare symptom burden between groups using the newly developed, self-rating, 12-item, Malmö POTS Score (MAPS; 0-10 per item, total range 0-120) based on patients’ own perception of symptoms through visual analogue scale assessment. We have also explored correlations between symptom severity assessed by MAPS, basic... (More)
Background
Postural orthostatic tachycardia syndrome (POTS) is a common cardiovascular autonomic disorder characterized by excessive heart rate increase on standing and symptoms of orthostatic intolerance, posing significant limitations on functional capacity. No objective tool exists to classify symptom burden in POTS.

Methods
We conducted a case-control study in 62 POTS patients and 50 healthy controls to compare symptom burden between groups using the newly developed, self-rating, 12-item, Malmö POTS Score (MAPS; 0-10 per item, total range 0-120) based on patients’ own perception of symptoms through visual analogue scale assessment. We have also explored correlations between symptom severity assessed by MAPS, basic clinical parameters and postural haemodynamic changes.

Results
POTS patients showed significantly higher total MAPS score (78±20 vs. 14±12, p
Conclusions
Symptom severity, as assessed by MAPS score, is 5-fold higher in POTS compared with healthy individuals. The new MAPS score can be useful as a semi-quantitative system to assess symptom burden, monitor disease progression and evaluate pre-test likelihood of disease. (Less)
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
POTS, Postural orthostatic tachycardia syndrome, Symptom burden, case-control study
in
European Heart Journal, Supplement
volume
24
issue
Supplement K
article number
suac121.072
publisher
Oxford University Press
conference name
Annual Congress of Italian Society of Cardiology
conference location
Rome, Italy
conference dates
2022-12-15 - 2022-12-18
ISSN
1520-765X
DOI
10.1093/eurheartjsupp/suac121.072
language
English
LU publication?
yes
id
97486e90-8fdd-4ab8-a329-0a541b6a66b3
date added to LUP
2022-12-21 10:58:37
date last changed
2022-12-23 02:32:27
@misc{97486e90-8fdd-4ab8-a329-0a541b6a66b3,
  abstract     = {{Background<br/>Postural orthostatic tachycardia syndrome (POTS) is a common cardiovascular autonomic disorder characterized by excessive heart rate increase on standing and symptoms of orthostatic intolerance, posing significant limitations on functional capacity. No objective tool exists to classify symptom burden in POTS.<br/><br/>Methods<br/>We conducted a case-control study in 62 POTS patients and 50 healthy controls to compare symptom burden between groups using the newly developed, self-rating, 12-item, Malmö POTS Score (MAPS; 0-10 per item, total range 0-120) based on patients’ own perception of symptoms through visual analogue scale assessment. We have also explored correlations between symptom severity assessed by MAPS, basic clinical parameters and postural haemodynamic changes.<br/><br/>Results<br/>POTS patients showed significantly higher total MAPS score (78±20 vs. 14±12, p<br/>Conclusions<br/>Symptom severity, as assessed by MAPS score, is 5-fold higher in POTS compared with healthy individuals. The new MAPS score can be useful as a semi-quantitative system to assess symptom burden, monitor disease progression and evaluate pre-test likelihood of disease.}},
  author       = {{Medic Spahic, Jasmina and Hamrefors, Viktor and Johansson, Madeleine and Ricci, Fabrizio and Melander, Olle and Sutton, Richard and Fedorowski, Artur}},
  issn         = {{1520-765X}},
  keywords     = {{POTS; Postural orthostatic tachycardia syndrome; Symptom burden; case-control study}},
  language     = {{eng}},
  note         = {{Conference Abstract}},
  number       = {{Supplement K}},
  publisher    = {{Oxford University Press}},
  series       = {{European Heart Journal, Supplement}},
  title        = {{Malmö POTS symptom score : Assessing symptom burden in postural orthostatic tachycardia syndrome}},
  url          = {{http://dx.doi.org/10.1093/eurheartjsupp/suac121.072}},
  doi          = {{10.1093/eurheartjsupp/suac121.072}},
  volume       = {{24}},
  year         = {{2022}},
}