Malmö POTS symptom score : Assessing symptom burden in postural orthostatic tachycardia syndrome
(2022) Annual Congress of Italian Society of Cardiology In European Heart Journal, Supplement 24(Supplement K).- Abstract
- Background
Postural orthostatic tachycardia syndrome (POTS) is a common cardiovascular autonomic disorder characterized by excessive heart rate increase on standing and symptoms of orthostatic intolerance, posing significant limitations on functional capacity. No objective tool exists to classify symptom burden in POTS.
Methods
We conducted a case-control study in 62 POTS patients and 50 healthy controls to compare symptom burden between groups using the newly developed, self-rating, 12-item, Malmö POTS Score (MAPS; 0-10 per item, total range 0-120) based on patients’ own perception of symptoms through visual analogue scale assessment. We have also explored correlations between symptom severity assessed by MAPS, basic... (More) - Background
Postural orthostatic tachycardia syndrome (POTS) is a common cardiovascular autonomic disorder characterized by excessive heart rate increase on standing and symptoms of orthostatic intolerance, posing significant limitations on functional capacity. No objective tool exists to classify symptom burden in POTS.
Methods
We conducted a case-control study in 62 POTS patients and 50 healthy controls to compare symptom burden between groups using the newly developed, self-rating, 12-item, Malmö POTS Score (MAPS; 0-10 per item, total range 0-120) based on patients’ own perception of symptoms through visual analogue scale assessment. We have also explored correlations between symptom severity assessed by MAPS, basic clinical parameters and postural haemodynamic changes.
Results
POTS patients showed significantly higher total MAPS score (78±20 vs. 14±12, p
Conclusions
Symptom severity, as assessed by MAPS score, is 5-fold higher in POTS compared with healthy individuals. The new MAPS score can be useful as a semi-quantitative system to assess symptom burden, monitor disease progression and evaluate pre-test likelihood of disease. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/97486e90-8fdd-4ab8-a329-0a541b6a66b3
- author
- Medic Spahic, Jasmina LU ; Hamrefors, Viktor LU ; Johansson, Madeleine LU ; Ricci, Fabrizio LU ; Melander, Olle LU ; Sutton, Richard and Fedorowski, Artur LU
- organization
- publishing date
- 2022-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- POTS, Postural orthostatic tachycardia syndrome, Symptom burden, case-control study
- in
- European Heart Journal, Supplement
- volume
- 24
- issue
- Supplement K
- article number
- suac121.072
- publisher
- Oxford University Press
- conference name
- Annual Congress of Italian Society of Cardiology
- conference location
- Rome, Italy
- conference dates
- 2022-12-15 - 2022-12-18
- ISSN
- 1520-765X
- DOI
- 10.1093/eurheartjsupp/suac121.072
- language
- English
- LU publication?
- yes
- id
- 97486e90-8fdd-4ab8-a329-0a541b6a66b3
- date added to LUP
- 2022-12-21 10:58:37
- date last changed
- 2022-12-23 02:32:27
@misc{97486e90-8fdd-4ab8-a329-0a541b6a66b3, abstract = {{Background<br/>Postural orthostatic tachycardia syndrome (POTS) is a common cardiovascular autonomic disorder characterized by excessive heart rate increase on standing and symptoms of orthostatic intolerance, posing significant limitations on functional capacity. No objective tool exists to classify symptom burden in POTS.<br/><br/>Methods<br/>We conducted a case-control study in 62 POTS patients and 50 healthy controls to compare symptom burden between groups using the newly developed, self-rating, 12-item, Malmö POTS Score (MAPS; 0-10 per item, total range 0-120) based on patients’ own perception of symptoms through visual analogue scale assessment. We have also explored correlations between symptom severity assessed by MAPS, basic clinical parameters and postural haemodynamic changes.<br/><br/>Results<br/>POTS patients showed significantly higher total MAPS score (78±20 vs. 14±12, p<br/>Conclusions<br/>Symptom severity, as assessed by MAPS score, is 5-fold higher in POTS compared with healthy individuals. The new MAPS score can be useful as a semi-quantitative system to assess symptom burden, monitor disease progression and evaluate pre-test likelihood of disease.}}, author = {{Medic Spahic, Jasmina and Hamrefors, Viktor and Johansson, Madeleine and Ricci, Fabrizio and Melander, Olle and Sutton, Richard and Fedorowski, Artur}}, issn = {{1520-765X}}, keywords = {{POTS; Postural orthostatic tachycardia syndrome; Symptom burden; case-control study}}, language = {{eng}}, note = {{Conference Abstract}}, number = {{Supplement K}}, publisher = {{Oxford University Press}}, series = {{European Heart Journal, Supplement}}, title = {{Malmö POTS symptom score : Assessing symptom burden in postural orthostatic tachycardia syndrome}}, url = {{http://dx.doi.org/10.1093/eurheartjsupp/suac121.072}}, doi = {{10.1093/eurheartjsupp/suac121.072}}, volume = {{24}}, year = {{2022}}, }