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Sclerosing mesenteritis and mesenteric panniculitis - clinical experience and radiological features

Nyberg, Lisa; Björk, Jan; Björkdahl, Peter LU ; Ekberg, Olle LU ; Sjöberg, Klas LU and Vigren, Lina LU (2017) In BMC Gastroenterology 17(1).
Abstract

Background: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Methods: Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study. Results: Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate... (More)

Background: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Methods: Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study. Results: Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate symptoms. This group with typical radiology was labelled MP. Four patients were included due to histologically verified disease but had uncharacteristic radiology involving multiple compartments of the abdomen. All four had marked systemic inflammation, fever and fluctuating radiologic findings. Three had severe disease with multiple hospitalisations and complications but responded promptly to corticosteroids. This group was denoted SM. Conclusions: We have identified two subgroups of patients; firstly, MP with stable and characteristic radiologic changes and secondly SM with atypical radiology and a more aggressive clinical course. We propose that the term SM should be reserved for this latter condition.

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author
organization
publishing date
type
Contribution to journal
publication status
published
keywords
Clinical classification, Mesenteric panniculitis, Mesenteritis, Panniculitis, Radiological classification, Retractile mesenteritis, Sclerosing mesenteritis
in
BMC Gastroenterology
volume
17
issue
1
publisher
BMC Biomedical Centre, Lund University
external identifiers
  • scopus:85020676301
  • wos:000403642500001
ISSN
1471-230X
DOI
10.1186/s12876-017-0632-7
language
English
LU publication?
yes
id
98f3bd8e-7d5f-4450-aa94-c81643ca303d
date added to LUP
2017-08-11 15:28:41
date last changed
2018-11-04 04:31:11
@article{98f3bd8e-7d5f-4450-aa94-c81643ca303d,
  abstract     = {<p>Background: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Methods: Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study. Results: Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate symptoms. This group with typical radiology was labelled MP. Four patients were included due to histologically verified disease but had uncharacteristic radiology involving multiple compartments of the abdomen. All four had marked systemic inflammation, fever and fluctuating radiologic findings. Three had severe disease with multiple hospitalisations and complications but responded promptly to corticosteroids. This group was denoted SM. Conclusions: We have identified two subgroups of patients; firstly, MP with stable and characteristic radiologic changes and secondly SM with atypical radiology and a more aggressive clinical course. We propose that the term SM should be reserved for this latter condition.</p>},
  articleno    = {75},
  author       = {Nyberg, Lisa and Björk, Jan and Björkdahl, Peter and Ekberg, Olle and Sjöberg, Klas and Vigren, Lina},
  issn         = {1471-230X},
  keyword      = {Clinical classification,Mesenteric panniculitis,Mesenteritis,Panniculitis,Radiological classification,Retractile mesenteritis,Sclerosing mesenteritis},
  language     = {eng},
  month        = {06},
  number       = {1},
  publisher    = {BMC Biomedical Centre, Lund University},
  series       = {BMC Gastroenterology},
  title        = {Sclerosing mesenteritis and mesenteric panniculitis - clinical experience and radiological features},
  url          = {http://dx.doi.org/10.1186/s12876-017-0632-7},
  volume       = {17},
  year         = {2017},
}