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A pilot study of facial, cranial and brain MRI morphometry in men with schizophrenia: Part 2.

Henriksson, Karin LU ; Wickstrom, Karin; Maltesson, Nils; Ericsson, Anders LU ; Karlsson, Johan LU ; Lindgren, Finn LU ; Åström, Karl LU ; McNeil, Thomas LU and Agartz, Ingrid (2006) In Psychiatry Research 147(2-3). p.187-195
Abstract
This pilot study applies a new 3D morphometric MR method to test the hypothesis that men with schizophrenia (vs. controls) have deviant facial shapes and landmark relations in cranio/facialibrain (CFB) regions. This constitutes Part 2 of paired articles in this issue of Psychiatry Research: Neuroimaging, in which Part 1 presents the new method in detail. MRI coordinates from CFB landmarks of 23 patients and 15 controls were identified and then aligned with the Procrustes model, leaving shape as the only unitless geometrical information. Men with schizophrenia had significantly longer mid- and lower-facial heights, and greater lower (left) facial depth, with a tendency toward rotation along the facial midline. This supports findings from... (More)
This pilot study applies a new 3D morphometric MR method to test the hypothesis that men with schizophrenia (vs. controls) have deviant facial shapes and landmark relations in cranio/facialibrain (CFB) regions. This constitutes Part 2 of paired articles in this issue of Psychiatry Research: Neuroimaging, in which Part 1 presents the new method in detail. MRI coordinates from CFB landmarks of 23 patients and 15 controls were identified and then aligned with the Procrustes model, leaving shape as the only unitless geometrical information. Men with schizophrenia had significantly longer mid- and lower-facial heights, and greater lower (left) facial depth, with a tendency toward rotation along the facial midline. This supports findings from earlier anthropometric and 3D studies of the "exterior" (face). In contrast, none of the patient-control differences for the new "interior" (cranial-brain) distances reached statistical significance. These results need to be retested on a larger sample of both sexes. (c) 2006 Elsevier Ireland Ltd. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
morphometry, magnetic resonance imaging, schizophrenia, shape, cranio-facial landmarks
in
Psychiatry Research
volume
147
issue
2-3
pages
187 - 195
publisher
Elsevier
external identifiers
  • wos:000241326800010
  • scopus:33748858507
ISSN
1872-7123
DOI
10.1016/j.pscychresns.2006.03.004
language
English
LU publication?
yes
id
9a649fcd-1401-4e28-a7b2-fc973d575154 (old id 161293)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16949799&dopt=Abstract
date added to LUP
2007-07-12 08:38:18
date last changed
2019-03-05 01:39:40
@article{9a649fcd-1401-4e28-a7b2-fc973d575154,
  abstract     = {This pilot study applies a new 3D morphometric MR method to test the hypothesis that men with schizophrenia (vs. controls) have deviant facial shapes and landmark relations in cranio/facialibrain (CFB) regions. This constitutes Part 2 of paired articles in this issue of Psychiatry Research: Neuroimaging, in which Part 1 presents the new method in detail. MRI coordinates from CFB landmarks of 23 patients and 15 controls were identified and then aligned with the Procrustes model, leaving shape as the only unitless geometrical information. Men with schizophrenia had significantly longer mid- and lower-facial heights, and greater lower (left) facial depth, with a tendency toward rotation along the facial midline. This supports findings from earlier anthropometric and 3D studies of the "exterior" (face). In contrast, none of the patient-control differences for the new "interior" (cranial-brain) distances reached statistical significance. These results need to be retested on a larger sample of both sexes. (c) 2006 Elsevier Ireland Ltd. All rights reserved.},
  author       = {Henriksson, Karin and Wickstrom, Karin and Maltesson, Nils and Ericsson, Anders and Karlsson, Johan and Lindgren, Finn and Åström, Karl and McNeil, Thomas and Agartz, Ingrid},
  issn         = {1872-7123},
  keyword      = {morphometry,magnetic resonance imaging,schizophrenia,shape,cranio-facial landmarks},
  language     = {eng},
  number       = {2-3},
  pages        = {187--195},
  publisher    = {Elsevier},
  series       = {Psychiatry Research},
  title        = {A pilot study of facial, cranial and brain MRI morphometry in men with schizophrenia: Part 2.},
  url          = {http://dx.doi.org/10.1016/j.pscychresns.2006.03.004},
  volume       = {147},
  year         = {2006},
}