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Improved general and oral health in diabetic patients by an okinawan-based nordic diet : A pilot study

Holmer, Helene LU ; Widén, Cecilia; Bengtsson, Viveca Wallin LU ; Coleman, Michael; Wohlfart, Björn LU ; Steen, Stig LU ; Persson, Rutger and Sjöberg, Klas LU (2018) In International Journal of Molecular Sciences 19(7).
Abstract

Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND®). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce... (More)

Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND®). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND®. The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15–63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND® (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND® thus showed significant promise in alleviating the impact of diabetes on dental as well as general health.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bleeding on probing, Clinical study, Cytokines, Diet, Metabolic disorder, Oral health
in
International Journal of Molecular Sciences
volume
19
issue
7
publisher
MOLECULAR DIVERSITY PRESERVATION INT
external identifiers
  • scopus:85049638140
ISSN
1661-6596
DOI
10.3390/ijms19071949
language
English
LU publication?
yes
id
9d364e67-0e7b-4da1-aaf6-b4a3b2c4f655
date added to LUP
2018-07-23 10:09:46
date last changed
2019-02-20 11:22:46
@article{9d364e67-0e7b-4da1-aaf6-b4a3b2c4f655,
  abstract     = {<p>Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND®). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND®. The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15–63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND® (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND® thus showed significant promise in alleviating the impact of diabetes on dental as well as general health.</p>},
  articleno    = {1949},
  author       = {Holmer, Helene and Widén, Cecilia and Bengtsson, Viveca Wallin and Coleman, Michael and Wohlfart, Björn and Steen, Stig and Persson, Rutger and Sjöberg, Klas},
  issn         = {1661-6596},
  keyword      = {Bleeding on probing,Clinical study,Cytokines,Diet,Metabolic disorder,Oral health},
  language     = {eng},
  month        = {07},
  number       = {7},
  publisher    = {MOLECULAR DIVERSITY PRESERVATION INT},
  series       = {International Journal of Molecular Sciences},
  title        = {Improved general and oral health in diabetic patients by an okinawan-based nordic diet : A pilot study},
  url          = {http://dx.doi.org/10.3390/ijms19071949},
  volume       = {19},
  year         = {2018},
}