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Therapeutic Potential of Iridoid Derivatives: Patent Review.

Raza, Muhammad Liaquat LU ; Hussain, Hidayat ; Green, Ivan R. ; Saleem, Muhammad and Nazir, Mamona (2019) In Inventions 4(2).
Abstract
Iridoids belong to a family of monoterpenoids comprising the cyclopentan[c]-pyran system; this class of compounds offers a wide range of biological effects, namely antileishmanial, anticancer, antiplasmodial, and anti-inflammatory potency. To date, a large number of biologically active iridoid derivatives have been reported from various plant families, including Rubiaceae, Plantaginaceae, Scrophulariaceae, and Verbenaceae. Furthermore, iridoids have the potential to form conjugates with other anticancer, antidiabetic, antileishmanial, and antimalarial drugs which synergistically have the potential to increase their effects. Additionally, future research should focus on the synthesis of halo analogs as well as preparing homo dimers or... (More)
Iridoids belong to a family of monoterpenoids comprising the cyclopentan[c]-pyran system; this class of compounds offers a wide range of biological effects, namely antileishmanial, anticancer, antiplasmodial, and anti-inflammatory potency. To date, a large number of biologically active iridoid derivatives have been reported from various plant families, including Rubiaceae, Plantaginaceae, Scrophulariaceae, and Verbenaceae. Furthermore, iridoids have the potential to form conjugates with other anticancer, antidiabetic, antileishmanial, and antimalarial drugs which synergistically have the potential to increase their effects. Additionally, future research should focus on the synthesis of halo analogs as well as preparing homo dimers or heterodimers of iridoids, since these might quite conceivably possess an increased bioactivity. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Inventions
volume
4
issue
2
article number
29
publisher
MDPI AG
external identifiers
  • scopus:85067894807
ISSN
2411-5134
DOI
10.3390/inventions4020029
language
English
LU publication?
yes
id
9d45d58a-931d-40a7-93c2-dbe9f5a70288
date added to LUP
2019-06-14 19:21:45
date last changed
2020-01-13 02:01:36
@article{9d45d58a-931d-40a7-93c2-dbe9f5a70288,
  abstract     = {Iridoids belong to a family of monoterpenoids comprising the cyclopentan[c]-pyran system; this class of compounds offers a wide range of biological effects, namely antileishmanial, anticancer, antiplasmodial, and anti-inflammatory potency. To date, a large number of biologically active iridoid derivatives have been reported from various plant families, including Rubiaceae, Plantaginaceae, Scrophulariaceae, and Verbenaceae. Furthermore, iridoids have the potential to form conjugates with other anticancer, antidiabetic, antileishmanial, and antimalarial drugs which synergistically have the potential to increase their effects. Additionally, future research should focus on the synthesis of halo analogs as well as preparing homo dimers or heterodimers of iridoids, since these might quite conceivably possess an increased bioactivity.},
  author       = {Raza, Muhammad Liaquat and Hussain, Hidayat  and Green, Ivan R. and Saleem, Muhammad and Nazir, Mamona},
  issn         = {2411-5134},
  language     = {eng},
  number       = {2},
  publisher    = {MDPI AG},
  series       = {Inventions},
  title        = {Therapeutic Potential of Iridoid Derivatives: Patent Review.},
  url          = {http://dx.doi.org/10.3390/inventions4020029},
  doi          = {10.3390/inventions4020029},
  volume       = {4},
  year         = {2019},
}